TY - JOUR
T1 - Opiate antagonists and the modification of heroin self administration behavior in man
T2 - an experimental study
AU - Altman, J. L.
AU - Meyer, R. E.
AU - Mirin, S. M.
AU - McNamee, H. B.
PY - 1976/1/1
Y1 - 1976/1/1
N2 - The heroin self administration behavior of 8 inpatient heroin addicts was examined for 10 days under blocked (i.e., following ingestion of narcotic antagonists naloxone or naltrexone) and unblocked (no antagonist) conditions. In the unblocked state, subjects injected all the available heroin, but they ceased heroin use almost completely following antagonist administration. Possible explanations for these results are discussed along with their implications for treatment.
AB - The heroin self administration behavior of 8 inpatient heroin addicts was examined for 10 days under blocked (i.e., following ingestion of narcotic antagonists naloxone or naltrexone) and unblocked (no antagonist) conditions. In the unblocked state, subjects injected all the available heroin, but they ceased heroin use almost completely following antagonist administration. Possible explanations for these results are discussed along with their implications for treatment.
UR - http://www.scopus.com/inward/record.url?scp=0017115772&partnerID=8YFLogxK
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U2 - 10.3109/10826087609056165
DO - 10.3109/10826087609056165
M3 - Article
C2 - 184054
AN - SCOPUS:0017115772
VL - 11
SP - 485
EP - 499
JO - [No source information available]
JF - [No source information available]
SN - 0042-1215
IS - 3
ER -