Opiate use and sexual function

S. M. Mirin, R. E. Meyer, J. H. Mendelson, J. Ellingboe

Research output: Contribution to journalArticle

91 Scopus citations

Abstract

Although opiate addicts often equate the drug experience with sexual orgasm, diminished libido and impaired sexual performance are common sequelae of chronic use. Early clinical studies suggested that opiates may interfere with sex hormone secretion. The authors carried out three sequential studies which demonstrated that heroin use in man results in acute suppression of luteinizing hormone (LH) release from the pituitary followed by a secondary drop in plasma testosterone levels. The time course of these neuroendocrine events correlates well with the tension-reducing effects of heroin and suggests that drive reduction is an important component of opiate reinforcement.

Original languageEnglish (US)
Pages (from-to)909-915
Number of pages7
JournalAmerican Journal of Psychiatry
Volume137
Issue number8
DOIs
StatePublished - Jan 1 1980

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'Opiate use and sexual function'. Together they form a unique fingerprint.

  • Cite this

    Mirin, S. M., Meyer, R. E., Mendelson, J. H., & Ellingboe, J. (1980). Opiate use and sexual function. American Journal of Psychiatry, 137(8), 909-915. https://doi.org/10.1176/ajp.137.8.909