Optic nerve regeneration in goldfish under light deprivation

Donald S. Leitner, Andrew Francis, M. S. Gazzaniga

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Regeneration following bilateral optic nerve crush was studied in groups of goldfish housed either on a standard diurnal cycle or under total light deprivation. Unoperated fish were included in each deprivation condition. Regeneration was only slightly delayed in the surgical group housed under light deprivation (68-81 days), compared to fish undergoing regeneration on the diurnal cycle (59-63 days). Visual capacity, as judged by days to meet criterion on a visual pattern dicrimination task, was unrelated to deprivation condition, but significantly lessened in fish having regenerated optic nerves. These results are discussed in terms of visual acuity following optic nerve regeneration and mechanisms of axonal reconnection.

Original languageEnglish (US)
Pages (from-to)105-107
Number of pages3
JournalBrain Research Bulletin
Volume8
Issue number1
DOIs
StatePublished - Jan 1982

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

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