Optical Fourier techniques for medical image processing and phase contrast imaging

Chandra S. Yelleswarapu, Sri-Rajasekhar Kothapalli, D. V.G.L.N. Rao

Research output: Contribution to journalArticle

34 Scopus citations


This paper briefly reviews the basics of optical Fourier techniques (OFT) and applications for medical image processing as well as phase contrast imaging of live biological specimens. Enhancement of microcalcifications in a mammogram for early diagnosis of breast cancer is the main focus. Various spatial filtering techniques such as conventional 4f filtering using a spatial mask, photoinduced polarization rotation in photosensitive materials, Fourier holography, and nonlinear transmission characteristics of optical materials are discussed for processing mammograms. We also reviewed how the intensity dependent refractive index can be exploited as a phase filter for phase contrast imaging with a coherent source. This novel approach represents a significant advance in phase contrast microscopy.

Original languageEnglish (US)
Pages (from-to)1876-1888
Number of pages13
JournalOptics Communications
Issue number7
Publication statusPublished - Apr 1 2008


All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Physical and Theoretical Chemistry
  • Electrical and Electronic Engineering

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