Optix drives the repeated convergent evolution of butterfly wing pattern mimicry

Robert D. Reed, Riccardo Papa, Arnaud Martin, Heather M. Hines, Brian A. Counterman, Carolina Pardo-Diaz, Chris D. Jiggins, Nicola L. Chamberlain, Marcus R. Kronforst, Rui Chen, Georg Halder, H. Frederik Nijhout, W. Owen McMillan

Research output: Contribution to journalArticle

212 Citations (Scopus)

Abstract

Mimicry - whereby warning signals in different species evolve to look similar - has long served as a paradigm of convergent evolution. Little is known, however, about the genes that underlie the evolution of mimetic phenotypes or to what extent the same or different genes drive such convergence. Here, we characterize one of the major genes responsible for mimetic wing pattern evolution in Heliconius butterflies. Mapping, gene expression, and population genetic work all identify a single gene, optix, that controls extreme red wing pattern variation across multiple species of Heliconius. Our results show that the cis-regulatory evolution of a single transcription factor can repeatedly drive the convergent evolution of complex color patterns in distantly related species, thus blurring the distinction between convergence and homology.

Original languageEnglish (US)
Pages (from-to)1137-1141
Number of pages5
JournalScience
Volume333
Issue number6046
DOIs
StatePublished - Aug 26 2011

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Butterflies
Genes
Population Genetics
Transcription Factors
Color
Phenotype
Gene Expression

All Science Journal Classification (ASJC) codes

  • General

Cite this

Reed, R. D., Papa, R., Martin, A., Hines, H. M., Counterman, B. A., Pardo-Diaz, C., ... McMillan, W. O. (2011). Optix drives the repeated convergent evolution of butterfly wing pattern mimicry. Science, 333(6046), 1137-1141. https://doi.org/10.1126/science.1208227
Reed, Robert D. ; Papa, Riccardo ; Martin, Arnaud ; Hines, Heather M. ; Counterman, Brian A. ; Pardo-Diaz, Carolina ; Jiggins, Chris D. ; Chamberlain, Nicola L. ; Kronforst, Marcus R. ; Chen, Rui ; Halder, Georg ; Nijhout, H. Frederik ; McMillan, W. Owen. / Optix drives the repeated convergent evolution of butterfly wing pattern mimicry. In: Science. 2011 ; Vol. 333, No. 6046. pp. 1137-1141.
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Reed, RD, Papa, R, Martin, A, Hines, HM, Counterman, BA, Pardo-Diaz, C, Jiggins, CD, Chamberlain, NL, Kronforst, MR, Chen, R, Halder, G, Nijhout, HF & McMillan, WO 2011, 'Optix drives the repeated convergent evolution of butterfly wing pattern mimicry', Science, vol. 333, no. 6046, pp. 1137-1141. https://doi.org/10.1126/science.1208227

Optix drives the repeated convergent evolution of butterfly wing pattern mimicry. / Reed, Robert D.; Papa, Riccardo; Martin, Arnaud; Hines, Heather M.; Counterman, Brian A.; Pardo-Diaz, Carolina; Jiggins, Chris D.; Chamberlain, Nicola L.; Kronforst, Marcus R.; Chen, Rui; Halder, Georg; Nijhout, H. Frederik; McMillan, W. Owen.

In: Science, Vol. 333, No. 6046, 26.08.2011, p. 1137-1141.

Research output: Contribution to journalArticle

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Reed RD, Papa R, Martin A, Hines HM, Counterman BA, Pardo-Diaz C et al. Optix drives the repeated convergent evolution of butterfly wing pattern mimicry. Science. 2011 Aug 26;333(6046):1137-1141. https://doi.org/10.1126/science.1208227