Oral amino-acid provision does not affect muscle strength or size gains in older men

Michael P. Godard, David L. Williamson, Scott W. Trappe

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Purpose: The intent of this investigation was to examine the effects of a daily oral provision consisting of amino acids (L-lysine, L-leucine, L-valine, L-phenylalanine, L-threonine, L-histidine, L-isoleucine, and L-methionine) in combination with carbohydrates (dextrose, sucrose, and fructose) on whole muscle strength and size characteristics during a 12-wk progressive knee extensor resistance training (PRT) program in older men (>65 yr). Methods: Seventeen older men were randomly assigned to either the experimental (EX) or control (CN) groups. The EX (N = 8) and CN (N = 9) groups had the following characteristics-EX: 70.8 ± 1.5 yr, 91.0 ± 4.9 kg, and 177.0 ± 3.9 cm; CN: 72.1 ± 1.9 yr, 75.4 ± 4.7 kg, and 176.1 ± 3.0. Pre and post PRT maximal unilateral isometric torque (N·m), isokinetic torque (1.05, 1.57, 2.09, 3.14, 4.19, and and 5.24 rad·s-1), work capacity (30 consecutive reps at 3.14 rad·s-1) torque, one repetition maximum (1RM) bilateral isotonic strength, and whole muscle cross-sectional area (CSA) of the mid-thigh were performed by computed tomography on each subject. Results: All variables showed and improvement with training (P < 0.05); however, there were no differences between the groups. Both groups increased in isometric strength by 21%, and isokinetic torque by 24% to 11% with the varying velocities (1.05-5.24 rad·s-1). Whole muscle 1RM strength and thigh CSA increased 50% and 6.5%, respectively. Additionally, voluntary torque/CSA increased 12% in both the EX and CN groups (P < 0.05). Conclusions: In conclusion, these data suggest that whole muscle strength and size are not enhanced with a postexercise daily provision of an oral amino-acid complex during 12 wk of PRT in older men.

Original languageEnglish (US)
Pages (from-to)1126-1131
Number of pages6
JournalMedicine and science in sports and exercise
Volume34
Issue number7
DOIs
StatePublished - Jan 1 2002

Fingerprint

Torque
Muscle Strength
Amino Acids
Thigh
Control Groups
Resistance Training
Isoleucine
Valine
Threonine
Fructose
Phenylalanine
Histidine
Leucine
Methionine
Lysine
Sucrose
Knee
Tomography
Carbohydrates
Education

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

@article{752b120f796a4dd584cfab00b04cfd61,
title = "Oral amino-acid provision does not affect muscle strength or size gains in older men",
abstract = "Purpose: The intent of this investigation was to examine the effects of a daily oral provision consisting of amino acids (L-lysine, L-leucine, L-valine, L-phenylalanine, L-threonine, L-histidine, L-isoleucine, and L-methionine) in combination with carbohydrates (dextrose, sucrose, and fructose) on whole muscle strength and size characteristics during a 12-wk progressive knee extensor resistance training (PRT) program in older men (>65 yr). Methods: Seventeen older men were randomly assigned to either the experimental (EX) or control (CN) groups. The EX (N = 8) and CN (N = 9) groups had the following characteristics-EX: 70.8 ± 1.5 yr, 91.0 ± 4.9 kg, and 177.0 ± 3.9 cm; CN: 72.1 ± 1.9 yr, 75.4 ± 4.7 kg, and 176.1 ± 3.0. Pre and post PRT maximal unilateral isometric torque (N·m), isokinetic torque (1.05, 1.57, 2.09, 3.14, 4.19, and and 5.24 rad·s-1), work capacity (30 consecutive reps at 3.14 rad·s-1) torque, one repetition maximum (1RM) bilateral isotonic strength, and whole muscle cross-sectional area (CSA) of the mid-thigh were performed by computed tomography on each subject. Results: All variables showed and improvement with training (P < 0.05); however, there were no differences between the groups. Both groups increased in isometric strength by 21{\%}, and isokinetic torque by 24{\%} to 11{\%} with the varying velocities (1.05-5.24 rad·s-1). Whole muscle 1RM strength and thigh CSA increased 50{\%} and 6.5{\%}, respectively. Additionally, voluntary torque/CSA increased 12{\%} in both the EX and CN groups (P < 0.05). Conclusions: In conclusion, these data suggest that whole muscle strength and size are not enhanced with a postexercise daily provision of an oral amino-acid complex during 12 wk of PRT in older men.",
author = "Godard, {Michael P.} and Williamson, {David L.} and Trappe, {Scott W.}",
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Oral amino-acid provision does not affect muscle strength or size gains in older men. / Godard, Michael P.; Williamson, David L.; Trappe, Scott W.

In: Medicine and science in sports and exercise, Vol. 34, No. 7, 01.01.2002, p. 1126-1131.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Oral amino-acid provision does not affect muscle strength or size gains in older men

AU - Godard, Michael P.

AU - Williamson, David L.

AU - Trappe, Scott W.

PY - 2002/1/1

Y1 - 2002/1/1

N2 - Purpose: The intent of this investigation was to examine the effects of a daily oral provision consisting of amino acids (L-lysine, L-leucine, L-valine, L-phenylalanine, L-threonine, L-histidine, L-isoleucine, and L-methionine) in combination with carbohydrates (dextrose, sucrose, and fructose) on whole muscle strength and size characteristics during a 12-wk progressive knee extensor resistance training (PRT) program in older men (>65 yr). Methods: Seventeen older men were randomly assigned to either the experimental (EX) or control (CN) groups. The EX (N = 8) and CN (N = 9) groups had the following characteristics-EX: 70.8 ± 1.5 yr, 91.0 ± 4.9 kg, and 177.0 ± 3.9 cm; CN: 72.1 ± 1.9 yr, 75.4 ± 4.7 kg, and 176.1 ± 3.0. Pre and post PRT maximal unilateral isometric torque (N·m), isokinetic torque (1.05, 1.57, 2.09, 3.14, 4.19, and and 5.24 rad·s-1), work capacity (30 consecutive reps at 3.14 rad·s-1) torque, one repetition maximum (1RM) bilateral isotonic strength, and whole muscle cross-sectional area (CSA) of the mid-thigh were performed by computed tomography on each subject. Results: All variables showed and improvement with training (P < 0.05); however, there were no differences between the groups. Both groups increased in isometric strength by 21%, and isokinetic torque by 24% to 11% with the varying velocities (1.05-5.24 rad·s-1). Whole muscle 1RM strength and thigh CSA increased 50% and 6.5%, respectively. Additionally, voluntary torque/CSA increased 12% in both the EX and CN groups (P < 0.05). Conclusions: In conclusion, these data suggest that whole muscle strength and size are not enhanced with a postexercise daily provision of an oral amino-acid complex during 12 wk of PRT in older men.

AB - Purpose: The intent of this investigation was to examine the effects of a daily oral provision consisting of amino acids (L-lysine, L-leucine, L-valine, L-phenylalanine, L-threonine, L-histidine, L-isoleucine, and L-methionine) in combination with carbohydrates (dextrose, sucrose, and fructose) on whole muscle strength and size characteristics during a 12-wk progressive knee extensor resistance training (PRT) program in older men (>65 yr). Methods: Seventeen older men were randomly assigned to either the experimental (EX) or control (CN) groups. The EX (N = 8) and CN (N = 9) groups had the following characteristics-EX: 70.8 ± 1.5 yr, 91.0 ± 4.9 kg, and 177.0 ± 3.9 cm; CN: 72.1 ± 1.9 yr, 75.4 ± 4.7 kg, and 176.1 ± 3.0. Pre and post PRT maximal unilateral isometric torque (N·m), isokinetic torque (1.05, 1.57, 2.09, 3.14, 4.19, and and 5.24 rad·s-1), work capacity (30 consecutive reps at 3.14 rad·s-1) torque, one repetition maximum (1RM) bilateral isotonic strength, and whole muscle cross-sectional area (CSA) of the mid-thigh were performed by computed tomography on each subject. Results: All variables showed and improvement with training (P < 0.05); however, there were no differences between the groups. Both groups increased in isometric strength by 21%, and isokinetic torque by 24% to 11% with the varying velocities (1.05-5.24 rad·s-1). Whole muscle 1RM strength and thigh CSA increased 50% and 6.5%, respectively. Additionally, voluntary torque/CSA increased 12% in both the EX and CN groups (P < 0.05). Conclusions: In conclusion, these data suggest that whole muscle strength and size are not enhanced with a postexercise daily provision of an oral amino-acid complex during 12 wk of PRT in older men.

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