Outcomes of a weight loss intervention among rural breast cancer survivors

Christie A. Befort, Jennifer R. Klemp, Heather L. Austin, Michael G. Perri, Kathryn Schmitz, Debra K. Sullivan, Carol J. Fabian

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

Obese breast cancer survivors have increased risk of recurrence and death compared to their normal weight counterparts. Rural women have significantly higher obesity rates, thus weight control intervention may be a key strategy for prevention of breast cancer recurrence in this population. This one-arm treatment study examined the impact of a group-based weight control intervention delivered through conference call technology to obese breast cancer survivors living in remote rural locations. The intervention included a reduced calorie diet incorporating prepackaged entrees and shakes, physical activity gradually increased to 225 min/week of moderate intensity exercise, and weekly group phone sessions. Outcomes included anthropomorphic, diet, physical activity, serum biomarker, and quality of life changes. Ninety-one percent of participants (31 of 34) attended >75% of intervention sessions and completed post-treatment data collection visits. At 6 months, significant changes were observed for weight (-12.5 ± 5.8 kg, 13.9% of baseline weight), waist circumference (-9.4 ± 6.3 cm), daily energy intake (-349 ± 550 kcal/day), fruits, and vegetables (+3.7 ± 4.3 servings/day), percent kcal from fat (-12.6 ± 8.6%), physical activity (+1235 ± 832 kcal/week; all P values <0.001), as well as significant reductions in fasting insulin (16.7% reduction, P = 0.006), and leptin (37.1% reduction, P < 0.001). Significant improvements were also seen for quality of life domains including mood, body image, and sexuality. In conclusion, the intervention produced >10% weight loss as well as significant improvements across multiple endpoints. The group phone-based treatment delivery approach may help disseminate effective weight control intervention to hard-to-reach breast cancer survivors.

Original languageEnglish (US)
Pages (from-to)631-639
Number of pages9
JournalBreast Cancer Research and Treatment
Volume132
Issue number2
DOIs
StatePublished - Apr 1 2012

Fingerprint

Survivors
Weight Loss
Breast Neoplasms
Weights and Measures
Exercise
Diet
Recurrence
Waist Circumference
Energy Intake
Vegetables
Fruit
Therapeutics
Obesity
Biomarkers
Fats
Quality of Life
Technology
Serum
Population

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Befort, C. A., Klemp, J. R., Austin, H. L., Perri, M. G., Schmitz, K., Sullivan, D. K., & Fabian, C. J. (2012). Outcomes of a weight loss intervention among rural breast cancer survivors. Breast Cancer Research and Treatment, 132(2), 631-639. https://doi.org/10.1007/s10549-011-1922-3
Befort, Christie A. ; Klemp, Jennifer R. ; Austin, Heather L. ; Perri, Michael G. ; Schmitz, Kathryn ; Sullivan, Debra K. ; Fabian, Carol J. / Outcomes of a weight loss intervention among rural breast cancer survivors. In: Breast Cancer Research and Treatment. 2012 ; Vol. 132, No. 2. pp. 631-639.
@article{40cbddf2ccee485280deb7fae14ce52e,
title = "Outcomes of a weight loss intervention among rural breast cancer survivors",
abstract = "Obese breast cancer survivors have increased risk of recurrence and death compared to their normal weight counterparts. Rural women have significantly higher obesity rates, thus weight control intervention may be a key strategy for prevention of breast cancer recurrence in this population. This one-arm treatment study examined the impact of a group-based weight control intervention delivered through conference call technology to obese breast cancer survivors living in remote rural locations. The intervention included a reduced calorie diet incorporating prepackaged entrees and shakes, physical activity gradually increased to 225 min/week of moderate intensity exercise, and weekly group phone sessions. Outcomes included anthropomorphic, diet, physical activity, serum biomarker, and quality of life changes. Ninety-one percent of participants (31 of 34) attended >75{\%} of intervention sessions and completed post-treatment data collection visits. At 6 months, significant changes were observed for weight (-12.5 ± 5.8 kg, 13.9{\%} of baseline weight), waist circumference (-9.4 ± 6.3 cm), daily energy intake (-349 ± 550 kcal/day), fruits, and vegetables (+3.7 ± 4.3 servings/day), percent kcal from fat (-12.6 ± 8.6{\%}), physical activity (+1235 ± 832 kcal/week; all P values <0.001), as well as significant reductions in fasting insulin (16.7{\%} reduction, P = 0.006), and leptin (37.1{\%} reduction, P < 0.001). Significant improvements were also seen for quality of life domains including mood, body image, and sexuality. In conclusion, the intervention produced >10{\%} weight loss as well as significant improvements across multiple endpoints. The group phone-based treatment delivery approach may help disseminate effective weight control intervention to hard-to-reach breast cancer survivors.",
author = "Befort, {Christie A.} and Klemp, {Jennifer R.} and Austin, {Heather L.} and Perri, {Michael G.} and Kathryn Schmitz and Sullivan, {Debra K.} and Fabian, {Carol J.}",
year = "2012",
month = "4",
day = "1",
doi = "10.1007/s10549-011-1922-3",
language = "English (US)",
volume = "132",
pages = "631--639",
journal = "Breast Cancer Research and Treatment",
issn = "0167-6806",
publisher = "Springer New York",
number = "2",

}

Befort, CA, Klemp, JR, Austin, HL, Perri, MG, Schmitz, K, Sullivan, DK & Fabian, CJ 2012, 'Outcomes of a weight loss intervention among rural breast cancer survivors', Breast Cancer Research and Treatment, vol. 132, no. 2, pp. 631-639. https://doi.org/10.1007/s10549-011-1922-3

Outcomes of a weight loss intervention among rural breast cancer survivors. / Befort, Christie A.; Klemp, Jennifer R.; Austin, Heather L.; Perri, Michael G.; Schmitz, Kathryn; Sullivan, Debra K.; Fabian, Carol J.

In: Breast Cancer Research and Treatment, Vol. 132, No. 2, 01.04.2012, p. 631-639.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Outcomes of a weight loss intervention among rural breast cancer survivors

AU - Befort, Christie A.

AU - Klemp, Jennifer R.

AU - Austin, Heather L.

AU - Perri, Michael G.

AU - Schmitz, Kathryn

AU - Sullivan, Debra K.

AU - Fabian, Carol J.

PY - 2012/4/1

Y1 - 2012/4/1

N2 - Obese breast cancer survivors have increased risk of recurrence and death compared to their normal weight counterparts. Rural women have significantly higher obesity rates, thus weight control intervention may be a key strategy for prevention of breast cancer recurrence in this population. This one-arm treatment study examined the impact of a group-based weight control intervention delivered through conference call technology to obese breast cancer survivors living in remote rural locations. The intervention included a reduced calorie diet incorporating prepackaged entrees and shakes, physical activity gradually increased to 225 min/week of moderate intensity exercise, and weekly group phone sessions. Outcomes included anthropomorphic, diet, physical activity, serum biomarker, and quality of life changes. Ninety-one percent of participants (31 of 34) attended >75% of intervention sessions and completed post-treatment data collection visits. At 6 months, significant changes were observed for weight (-12.5 ± 5.8 kg, 13.9% of baseline weight), waist circumference (-9.4 ± 6.3 cm), daily energy intake (-349 ± 550 kcal/day), fruits, and vegetables (+3.7 ± 4.3 servings/day), percent kcal from fat (-12.6 ± 8.6%), physical activity (+1235 ± 832 kcal/week; all P values <0.001), as well as significant reductions in fasting insulin (16.7% reduction, P = 0.006), and leptin (37.1% reduction, P < 0.001). Significant improvements were also seen for quality of life domains including mood, body image, and sexuality. In conclusion, the intervention produced >10% weight loss as well as significant improvements across multiple endpoints. The group phone-based treatment delivery approach may help disseminate effective weight control intervention to hard-to-reach breast cancer survivors.

AB - Obese breast cancer survivors have increased risk of recurrence and death compared to their normal weight counterparts. Rural women have significantly higher obesity rates, thus weight control intervention may be a key strategy for prevention of breast cancer recurrence in this population. This one-arm treatment study examined the impact of a group-based weight control intervention delivered through conference call technology to obese breast cancer survivors living in remote rural locations. The intervention included a reduced calorie diet incorporating prepackaged entrees and shakes, physical activity gradually increased to 225 min/week of moderate intensity exercise, and weekly group phone sessions. Outcomes included anthropomorphic, diet, physical activity, serum biomarker, and quality of life changes. Ninety-one percent of participants (31 of 34) attended >75% of intervention sessions and completed post-treatment data collection visits. At 6 months, significant changes were observed for weight (-12.5 ± 5.8 kg, 13.9% of baseline weight), waist circumference (-9.4 ± 6.3 cm), daily energy intake (-349 ± 550 kcal/day), fruits, and vegetables (+3.7 ± 4.3 servings/day), percent kcal from fat (-12.6 ± 8.6%), physical activity (+1235 ± 832 kcal/week; all P values <0.001), as well as significant reductions in fasting insulin (16.7% reduction, P = 0.006), and leptin (37.1% reduction, P < 0.001). Significant improvements were also seen for quality of life domains including mood, body image, and sexuality. In conclusion, the intervention produced >10% weight loss as well as significant improvements across multiple endpoints. The group phone-based treatment delivery approach may help disseminate effective weight control intervention to hard-to-reach breast cancer survivors.

UR - http://www.scopus.com/inward/record.url?scp=84859062110&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84859062110&partnerID=8YFLogxK

U2 - 10.1007/s10549-011-1922-3

DO - 10.1007/s10549-011-1922-3

M3 - Article

C2 - 22198470

AN - SCOPUS:84859062110

VL - 132

SP - 631

EP - 639

JO - Breast Cancer Research and Treatment

JF - Breast Cancer Research and Treatment

SN - 0167-6806

IS - 2

ER -