Outcomes of AngioJet® thrombectomy in hemodialysis vascular access grafts and fistulas: PEARL I Registry

Eugene Simoni, Lawrence Blitz, Robert Lookstein

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Purpose: Results are reported from the PEARL I Registry for procedures where a mid-length AngioJet catheter was used for thrombosed hemodialysis arteriovenous grafts and fistulae. Methods: The PEARL I Registry was a prospective, multicenter, observational database collecting information on the AngioJet procedures for a variety of thrombotic conditions. Patient demographics, procedural information, outcome data, and safety information were collected through 3 months postprocedure on AngioJet procedures. This paper describes the data collected for subjects presenting with hemodialysis access thrombosis. Results: A total of 72 (16%) of the 452 subjects enrolled in the PEARL 1 Registry had thrombosed hemodialysis access sites. Procedural success was reported in 66/72 subjects (92%); surgical interventions were required in 6/72 subjects (8%). There was a statistically significant improvement (p<0.0001) in vessel occlusion from baseline to final angiography. Eighty-eight percent of access sites were patent at the end of the procedure and 97% of vessels showed improved occlusion status of ≥1 grades. Among prosthetic grafts, 53% (20/38) remained patent at the 3-month follow-up, 18% (7/38) were restenosed, and 29% (11/38) rethrombosed. Among autologous fistulas, 86% (18/21) remained patent without intervention at the 3-month follow-up; 3 fistulas rethrombosed. Four subjects (5%) died; none of the deaths were considered related to the AngioJet device or procedure. Conclusions: Outcomes from the PEARL I registry corroborate other studies of AngioJet thrombectomy and the overall literature of endovascular thrombectomy procedures. A high procedural success rates with acceptable near-term patency rates and low rates of adverse events are achieved with AngioJet thrombectomy.

Original languageEnglish (US)
Pages (from-to)72-76
Number of pages5
JournalJournal of Vascular Access
Volume14
Issue number1
DOIs
StatePublished - Mar 1 2013

Fingerprint

Thrombectomy
Fistula
Blood Vessels
Registries
Renal Dialysis
Transplants
Thrombosis
Endovascular Procedures
Arteriovenous Fistula
Angiography
Catheters
Demography
Databases
Safety
Equipment and Supplies

All Science Journal Classification (ASJC) codes

  • Surgery
  • Nephrology

Cite this

@article{e356425e4a1a4575b5f6a6321838151b,
title = "Outcomes of AngioJet{\circledR} thrombectomy in hemodialysis vascular access grafts and fistulas: PEARL I Registry",
abstract = "Purpose: Results are reported from the PEARL I Registry for procedures where a mid-length AngioJet catheter was used for thrombosed hemodialysis arteriovenous grafts and fistulae. Methods: The PEARL I Registry was a prospective, multicenter, observational database collecting information on the AngioJet procedures for a variety of thrombotic conditions. Patient demographics, procedural information, outcome data, and safety information were collected through 3 months postprocedure on AngioJet procedures. This paper describes the data collected for subjects presenting with hemodialysis access thrombosis. Results: A total of 72 (16{\%}) of the 452 subjects enrolled in the PEARL 1 Registry had thrombosed hemodialysis access sites. Procedural success was reported in 66/72 subjects (92{\%}); surgical interventions were required in 6/72 subjects (8{\%}). There was a statistically significant improvement (p<0.0001) in vessel occlusion from baseline to final angiography. Eighty-eight percent of access sites were patent at the end of the procedure and 97{\%} of vessels showed improved occlusion status of ≥1 grades. Among prosthetic grafts, 53{\%} (20/38) remained patent at the 3-month follow-up, 18{\%} (7/38) were restenosed, and 29{\%} (11/38) rethrombosed. Among autologous fistulas, 86{\%} (18/21) remained patent without intervention at the 3-month follow-up; 3 fistulas rethrombosed. Four subjects (5{\%}) died; none of the deaths were considered related to the AngioJet device or procedure. Conclusions: Outcomes from the PEARL I registry corroborate other studies of AngioJet thrombectomy and the overall literature of endovascular thrombectomy procedures. A high procedural success rates with acceptable near-term patency rates and low rates of adverse events are achieved with AngioJet thrombectomy.",
author = "Eugene Simoni and Lawrence Blitz and Robert Lookstein",
year = "2013",
month = "3",
day = "1",
doi = "10.5301/jva.5000102",
language = "English (US)",
volume = "14",
pages = "72--76",
journal = "Journal of Vascular Access",
issn = "1129-7298",
publisher = "Wichtig Publishing",
number = "1",

}

Outcomes of AngioJet® thrombectomy in hemodialysis vascular access grafts and fistulas : PEARL I Registry. / Simoni, Eugene; Blitz, Lawrence; Lookstein, Robert.

In: Journal of Vascular Access, Vol. 14, No. 1, 01.03.2013, p. 72-76.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Outcomes of AngioJet® thrombectomy in hemodialysis vascular access grafts and fistulas

T2 - PEARL I Registry

AU - Simoni, Eugene

AU - Blitz, Lawrence

AU - Lookstein, Robert

PY - 2013/3/1

Y1 - 2013/3/1

N2 - Purpose: Results are reported from the PEARL I Registry for procedures where a mid-length AngioJet catheter was used for thrombosed hemodialysis arteriovenous grafts and fistulae. Methods: The PEARL I Registry was a prospective, multicenter, observational database collecting information on the AngioJet procedures for a variety of thrombotic conditions. Patient demographics, procedural information, outcome data, and safety information were collected through 3 months postprocedure on AngioJet procedures. This paper describes the data collected for subjects presenting with hemodialysis access thrombosis. Results: A total of 72 (16%) of the 452 subjects enrolled in the PEARL 1 Registry had thrombosed hemodialysis access sites. Procedural success was reported in 66/72 subjects (92%); surgical interventions were required in 6/72 subjects (8%). There was a statistically significant improvement (p<0.0001) in vessel occlusion from baseline to final angiography. Eighty-eight percent of access sites were patent at the end of the procedure and 97% of vessels showed improved occlusion status of ≥1 grades. Among prosthetic grafts, 53% (20/38) remained patent at the 3-month follow-up, 18% (7/38) were restenosed, and 29% (11/38) rethrombosed. Among autologous fistulas, 86% (18/21) remained patent without intervention at the 3-month follow-up; 3 fistulas rethrombosed. Four subjects (5%) died; none of the deaths were considered related to the AngioJet device or procedure. Conclusions: Outcomes from the PEARL I registry corroborate other studies of AngioJet thrombectomy and the overall literature of endovascular thrombectomy procedures. A high procedural success rates with acceptable near-term patency rates and low rates of adverse events are achieved with AngioJet thrombectomy.

AB - Purpose: Results are reported from the PEARL I Registry for procedures where a mid-length AngioJet catheter was used for thrombosed hemodialysis arteriovenous grafts and fistulae. Methods: The PEARL I Registry was a prospective, multicenter, observational database collecting information on the AngioJet procedures for a variety of thrombotic conditions. Patient demographics, procedural information, outcome data, and safety information were collected through 3 months postprocedure on AngioJet procedures. This paper describes the data collected for subjects presenting with hemodialysis access thrombosis. Results: A total of 72 (16%) of the 452 subjects enrolled in the PEARL 1 Registry had thrombosed hemodialysis access sites. Procedural success was reported in 66/72 subjects (92%); surgical interventions were required in 6/72 subjects (8%). There was a statistically significant improvement (p<0.0001) in vessel occlusion from baseline to final angiography. Eighty-eight percent of access sites were patent at the end of the procedure and 97% of vessels showed improved occlusion status of ≥1 grades. Among prosthetic grafts, 53% (20/38) remained patent at the 3-month follow-up, 18% (7/38) were restenosed, and 29% (11/38) rethrombosed. Among autologous fistulas, 86% (18/21) remained patent without intervention at the 3-month follow-up; 3 fistulas rethrombosed. Four subjects (5%) died; none of the deaths were considered related to the AngioJet device or procedure. Conclusions: Outcomes from the PEARL I registry corroborate other studies of AngioJet thrombectomy and the overall literature of endovascular thrombectomy procedures. A high procedural success rates with acceptable near-term patency rates and low rates of adverse events are achieved with AngioJet thrombectomy.

UR - http://www.scopus.com/inward/record.url?scp=84871982694&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84871982694&partnerID=8YFLogxK

U2 - 10.5301/jva.5000102

DO - 10.5301/jva.5000102

M3 - Article

C2 - 22865534

AN - SCOPUS:84871982694

VL - 14

SP - 72

EP - 76

JO - Journal of Vascular Access

JF - Journal of Vascular Access

SN - 1129-7298

IS - 1

ER -