Abstract
Tissue oxygen pressure (ptO2) was measured with noble metal microelectrodes in hippocampal slices in vitro. During hypoxia, the ptO2 at 100 μm depth fell rapidly to less than 20 mm Hg. During reoxygenation, large transient ptO2 increases above normoxic values were observed. These data demonstrate that ptO2 'overshoots' occur independently of in situ posthypoxic hyperemia and may reflect pathologic chemical reactions in brain tissue during reoxygenation.
Original language | English (US) |
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Pages (from-to) | 150-153 |
Number of pages | 4 |
Journal | Brain research |
Volume | 344 |
Issue number | 1 |
DOIs | |
State | Published - Sep 30 1985 |
All Science Journal Classification (ASJC) codes
- Neuroscience(all)
- Molecular Biology
- Clinical Neurology
- Developmental Biology