Paediatric leptospirosis: A population based case-control study from Chennai, India

R. Narayanan, G. Sumathi, S. G. Prabhakaran, Shanmughapriya Santhanam, K. Natarajaseenivasan

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The surveillance in Chennai identified 134 children and 443 adults clinically suspected for leptospirosis. Of these, 35 (26.1%) children and 118 (26.6%) adults had laboratory confirmed diagnosis for leptospirosis. The paediatric leptospirosis exhibited a higher frequency of classic features of Weil's disease. The prevalent serovar encountered was Icterohaemorrhagiae with no difference in the pattern of infecting serovars between the two groups. Further, confirmation of diagnosis was achieved by polymerase chain reaction (PCR) with a positivity of 28.4% (specificity 96%). Univariate analysis showed significant association of paediatric leptospirosis with rat infestation (odds ratio 87.4). Thus, PCR facilitates early diagnosis of febrile illness among paediatric cases.

Original languageEnglish (US)
Pages (from-to)228-232
Number of pages5
JournalIndian Journal of Medical Microbiology
Volume34
Issue number2
DOIs
StatePublished - Apr 1 2016

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Leptospirosis
Case-Control Studies
India
Pediatrics
Population
Polymerase Chain Reaction
Clinical Laboratory Techniques
Early Diagnosis
Fever
Odds Ratio
Serogroup

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

Cite this

Narayanan, R. ; Sumathi, G. ; Prabhakaran, S. G. ; Santhanam, Shanmughapriya ; Natarajaseenivasan, K. / Paediatric leptospirosis : A population based case-control study from Chennai, India. In: Indian Journal of Medical Microbiology. 2016 ; Vol. 34, No. 2. pp. 228-232.
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Paediatric leptospirosis : A population based case-control study from Chennai, India. / Narayanan, R.; Sumathi, G.; Prabhakaran, S. G.; Santhanam, Shanmughapriya; Natarajaseenivasan, K.

In: Indian Journal of Medical Microbiology, Vol. 34, No. 2, 01.04.2016, p. 228-232.

Research output: Contribution to journalArticle

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