Palisading cutaneous fibrous histiocytoma: An immunohistochemical study demonstrating differentiation from dermal dendrocytes

Klaus Helm, T. Helm, F. Helm

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14 Scopus citations

Abstract

The palisading cutaneous fibrous histiocytoma is a unique benign spindle cell tumor that often occurs in an acral location. Histologic findings feature nuclear palisading reminiscent of a schwannoma. Previous studies have suggested that this tumor may be a variant of a dermatofibroma. We performed immunohistochemical staining with a panel of antibodies including neurofilament, S100 protein, factor XIIIa, epithelial membrane antigen, Leu- 7, desmin, and vimentin. We found positive staining with factor XIIIa and vimentin, suggesting connective tissue differentiation for this tumor.

Original languageEnglish (US)
Pages (from-to)559-561
Number of pages3
JournalAmerican Journal of Dermatopathology
Volume15
Issue number6
DOIs
StatePublished - Jan 1 1993

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Dermatology

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