Palliative effect of capecitabine and cetuximab for refractory metastatic squamous cell carcinoma of the perineum in epidermodysplasia verruciformis.

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Abstract

A teenage girl presented with multiple warty skin lesions and had a diagnosis of epidermodysplasia verruciformis made several years later. Later in life she presented with an extensive SCC in situ in her gluteal crease that was surgically resected with wide margins. Despite this treatment, the lesion recurred with extension onto her lower back. Biopsies at the time confirmed SCC in situ of the perianal tissue and invasive SCC above her gluteal cleft.

Original languageEnglish (US)
Pages (from-to)54-56
Number of pages3
JournalSkinmed
Volume12
Issue number1
StatePublished - 2014

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Epidermodysplasia Verruciformis
Perineum
Squamous Cell Carcinoma
Biopsy
Skin
Therapeutics
Capecitabine
Cetuximab

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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title = "Palliative effect of capecitabine and cetuximab for refractory metastatic squamous cell carcinoma of the perineum in epidermodysplasia verruciformis.",
abstract = "A teenage girl presented with multiple warty skin lesions and had a diagnosis of epidermodysplasia verruciformis made several years later. Later in life she presented with an extensive SCC in situ in her gluteal crease that was surgically resected with wide margins. Despite this treatment, the lesion recurred with extension onto her lower back. Biopsies at the time confirmed SCC in situ of the perianal tissue and invasive SCC above her gluteal cleft.",
author = "Lynch, {Michael C.} and Joseph Drabick and Rogerio Neves and Edward Fox and Heath Mackley and Bryan Anderson",
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T1 - Palliative effect of capecitabine and cetuximab for refractory metastatic squamous cell carcinoma of the perineum in epidermodysplasia verruciformis.

AU - Lynch, Michael C.

AU - Drabick, Joseph

AU - Neves, Rogerio

AU - Fox, Edward

AU - Mackley, Heath

AU - Anderson, Bryan

PY - 2014

Y1 - 2014

N2 - A teenage girl presented with multiple warty skin lesions and had a diagnosis of epidermodysplasia verruciformis made several years later. Later in life she presented with an extensive SCC in situ in her gluteal crease that was surgically resected with wide margins. Despite this treatment, the lesion recurred with extension onto her lower back. Biopsies at the time confirmed SCC in situ of the perianal tissue and invasive SCC above her gluteal cleft.

AB - A teenage girl presented with multiple warty skin lesions and had a diagnosis of epidermodysplasia verruciformis made several years later. Later in life she presented with an extensive SCC in situ in her gluteal crease that was surgically resected with wide margins. Despite this treatment, the lesion recurred with extension onto her lower back. Biopsies at the time confirmed SCC in situ of the perianal tissue and invasive SCC above her gluteal cleft.

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