Partial Splenic Embolization in the Treatment of Patients with Portal Hypertension

A Review of the English Language Literature

Kristen Gledhill Koconis, Harjit Singh, Gregory Soares

Research output: Contribution to journalReview article

61 Citations (Scopus)

Abstract

This article reviews the existing literature on the use of partial splenic embolization in patients with portal hypertension. All articles published in the English language on splenic embolization or partial splenic embolization as a treatment for portal hypertension were identified with a PubMed search from 1973 through 2005. Partial splenic embolization appears to be efficacious in reducing episodes of variceal bleeding, improving hematologic parameters, enhancing hepatic protein synthesis, and reducing the severity of hepatic encephalopathy. Associated morbidity and mortality appear to be acceptable. The literature, however, is limited in quality. Given the potential benefits of partial splenic embolization, further investigation is warranted to allow evidence-based evaluation of its use.

Original languageEnglish (US)
Pages (from-to)463-481
Number of pages19
JournalJournal of Vascular and Interventional Radiology
Volume18
Issue number4
DOIs
StatePublished - Apr 1 2007

Fingerprint

Portal Hypertension
Language
Hepatic Encephalopathy
PubMed
Hemorrhage
Morbidity
Mortality
Liver
Therapeutics
Proteins

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

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abstract = "This article reviews the existing literature on the use of partial splenic embolization in patients with portal hypertension. All articles published in the English language on splenic embolization or partial splenic embolization as a treatment for portal hypertension were identified with a PubMed search from 1973 through 2005. Partial splenic embolization appears to be efficacious in reducing episodes of variceal bleeding, improving hematologic parameters, enhancing hepatic protein synthesis, and reducing the severity of hepatic encephalopathy. Associated morbidity and mortality appear to be acceptable. The literature, however, is limited in quality. Given the potential benefits of partial splenic embolization, further investigation is warranted to allow evidence-based evaluation of its use.",
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Partial Splenic Embolization in the Treatment of Patients with Portal Hypertension : A Review of the English Language Literature. / Koconis, Kristen Gledhill; Singh, Harjit; Soares, Gregory.

In: Journal of Vascular and Interventional Radiology, Vol. 18, No. 4, 01.04.2007, p. 463-481.

Research output: Contribution to journalReview article

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