Patient-centered precision health in a learning health care system: Geisinger's genomic medicine experience

Marc S. Williams, Adam H. Buchanan, F. Daniel Davis, W. Andrew Faucett, Miranda L.G. Hallquist, Joseph B. Leader, Christa L. Martin, Cara Z. McCormick, Michelle N. Meyer, Michael F. Murray, Alanna K. Rahm, Marci L.B. Schwartz, Amy C. Sturm, Jennifer K. Wagner, Janet L. Williams, Huntington F. Willard, David H. Ledbetter

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Health care delivery is increasingly influenced by the emerging concepts of precision health and the learning health care system. Although not synonymous with precision health, genomics is a key enabler of individualized care. Delivering patient-centered, genomics-informed care based on individual-level data in the current national landscape of health care delivery is a daunting challenge. Problems to overcome include data generation, analysis, storage, and transfer; knowledge management and representation for patients and providers at the point of care; process management; and outcomes definition, collection, and analysis. Development, testing, and implementation of a genomics-informed program requires multidisciplinary collaboration and building the concepts of precision health into a multilevel implementation framework. Using the principles of a learning health care system provides a promising solution. This article describes the implementation of population-based genomic medicine in an integrated learning health care system-a working example of a precision health program.

Original languageEnglish (US)
Pages (from-to)757-764
Number of pages8
JournalHealth Affairs
Volume37
Issue number5
DOIs
StatePublished - 2018

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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