Patients' views on incidental findings from clinical exome sequencing

Kristin E. Clift, Colin M.E. Halverson, Alexander S. Fiksdal, Ashok Kumbamu, Richard R. Sharp, Jennifer McCormick

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

This article characterizes the opinions of patients and family members of patients undergoing clinical genomic-based testing regarding the return of incidental findings from these tests. Over sixteen months, we conducted 55 in-depth interviews with individuals to explore their preferences regarding which types of results they would like returned to them. Responses indicate a diversity of attitudes toward the return of incidental findings and a diversity of justifications for those attitudes. The majority of participants also described an imperative to include the patient in deciding which results to return rather than having universal, predetermined rules governing results disclosure. The results demonstrate the importance of a patient centered-approach to returning incidental findings.

Original languageEnglish (US)
Pages (from-to)38-43
Number of pages6
JournalApplied and Translational Genomics
Volume4
DOIs
StatePublished - Mar 1 2015

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Exome
Incidental Findings
Disclosure
Interviews

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Molecular Biology
  • Pharmaceutical Science

Cite this

Clift, Kristin E. ; Halverson, Colin M.E. ; Fiksdal, Alexander S. ; Kumbamu, Ashok ; Sharp, Richard R. ; McCormick, Jennifer. / Patients' views on incidental findings from clinical exome sequencing. In: Applied and Translational Genomics. 2015 ; Vol. 4. pp. 38-43.
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Patients' views on incidental findings from clinical exome sequencing. / Clift, Kristin E.; Halverson, Colin M.E.; Fiksdal, Alexander S.; Kumbamu, Ashok; Sharp, Richard R.; McCormick, Jennifer.

In: Applied and Translational Genomics, Vol. 4, 01.03.2015, p. 38-43.

Research output: Contribution to journalArticle

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