Pediatric Cardiopulmonary Bypass: Does Perfusion Mode Matter?

Jonathan J. Talor, Akif Ündar

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

This current review describes how components of the cardiopulmonary bypass (CPB) circuit are selected and examines the benefits of pulsatile perfusion for use during CPB. Pulsatile flow generates significantly greater surplus hemodynamic energy (SHE) than nonpulsatile flow; higher SHE values have been associated with better microcirculation perfusion, lower rates of systemic inflammatory response, and better vital organ protection. Pulsatile perfusion may have a positive effect on clinical outcomes, play a role in preserving homeostasis, and help to decrease morbidity associated with CPB.

Original languageEnglish (US)
Pages (from-to)296-300
Number of pages5
JournalWorld Journal for Pediatric and Congenital Heart Surgery
Volume2
Issue number2
DOIs
StatePublished - Apr 2011

Fingerprint

Pulsatile Flow
Cardiopulmonary Bypass
Perfusion
Pediatrics
Hemodynamics
Microcirculation
Homeostasis
Morbidity

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine

Cite this

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Pediatric Cardiopulmonary Bypass : Does Perfusion Mode Matter? / Talor, Jonathan J.; Ündar, Akif.

In: World Journal for Pediatric and Congenital Heart Surgery, Vol. 2, No. 2, 04.2011, p. 296-300.

Research output: Contribution to journalReview article

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