Peptide map analysis of mutant transplantation antigens

Sandra J. Ewald, Jan Klein, Leroy E. Hood

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

H-2K antigens from two histocompatibility mutants, M506 (H-2Kfa) and M523 (H-2Kka) and from their parental strains, A.CA (H-2kf) and CBA (H-2Kk), are compared by ion exchange chromatography of tryptic peptides. Both mutant molecules differ from their parental counterparts by only one or two peptides. These results are discussed with reference to the alterations in serological and biological properties exhibited by the two mutations.

Original languageEnglish (US)
Pages (from-to)551-559
Number of pages9
JournalImmunogenetics
Volume8
Issue number1
DOIs
StatePublished - Dec 1 1979

All Science Journal Classification (ASJC) codes

  • Immunology
  • Genetics

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