Performance differences between addicts and non-addicts

S. Rothenberg, S. Schottenfeld, R. E. Meyer, B. Krauss, K. Gross

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Methadone addicts and non-addict controls were tested before and after receiving up to 10 mg of methadone on simple visual reaction time tests and on a vigilance type visual attention test. Addicts were faster than controls on pre-drug testing, although there were no pre-drug differences between groups on the attention task. Addicts maintained faster reaction times than controls even when money was offered as an incentive for speed. Additional methadone did not affect addict performance on any of the tasks. Methadone slowed control reaction times in a doserelated fashion. No significant attention decrements were seen after methadone in controls. Visual reaction time differences between addicts and controls cannot be attributed to group differences in motivation or ability to attend. Slowing of reaction time with acute dose of methadone in controls cannot be attributed to the effect of the drug on attention. An hypothesized drug-induced decrease in visual sensitivity with acute dose in controls and a drug-induced increase in visual sensitivity with chronic dose in addicts can account for the presented data.

Original languageEnglish (US)
Pages (from-to)299-306
Number of pages8
JournalPsychopharmacology
Volume52
Issue number3
DOIs
StatePublished - Jan 1 1977

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Methadone
Reaction Time
Pharmaceutical Preparations
Motivation
Aptitude
Drug and Narcotic Control

All Science Journal Classification (ASJC) codes

  • Pharmacology

Cite this

Rothenberg, S., Schottenfeld, S., Meyer, R. E., Krauss, B., & Gross, K. (1977). Performance differences between addicts and non-addicts. Psychopharmacology, 52(3), 299-306. https://doi.org/10.1007/BF00426715
Rothenberg, S. ; Schottenfeld, S. ; Meyer, R. E. ; Krauss, B. ; Gross, K. / Performance differences between addicts and non-addicts. In: Psychopharmacology. 1977 ; Vol. 52, No. 3. pp. 299-306.
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Rothenberg, S, Schottenfeld, S, Meyer, RE, Krauss, B & Gross, K 1977, 'Performance differences between addicts and non-addicts', Psychopharmacology, vol. 52, no. 3, pp. 299-306. https://doi.org/10.1007/BF00426715

Performance differences between addicts and non-addicts. / Rothenberg, S.; Schottenfeld, S.; Meyer, R. E.; Krauss, B.; Gross, K.

In: Psychopharmacology, Vol. 52, No. 3, 01.01.1977, p. 299-306.

Research output: Contribution to journalArticle

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Rothenberg S, Schottenfeld S, Meyer RE, Krauss B, Gross K. Performance differences between addicts and non-addicts. Psychopharmacology. 1977 Jan 1;52(3):299-306. https://doi.org/10.1007/BF00426715