Perinatal outcomes in growth-restricted twins compared with age-matched growth-restricted singletons

Anthony O. Odibo, Raegan E. McDonald, David M. Stamilio, Serdar H. Ural, George A. Macones

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The objective of this study was to compare the perinatal outcomes in growth-restricted (IUGR) twins with a matched group of IUGR singletons. We performed a retrospective cohort study evaluating the perinatal outcomes in IUGR twins matched for gestational age at delivery to the next four IUGR singletons (1:4) in our perinatal database. The perinatal outcomes evaluated included rates of uncorrected perinatal mortality (PMR), admission to the neonatal intensive care unit (NICU), respiratory distress syndrome, grades 3 or 4 intraventricular hemorrhage, necrotizing enterocolitis, periventricular leukomalacia, and length of NICU stay. A cohort of twins with IUGR were matched with a cohort of IUGR singletons and compared for perinatal outcomes. A p value < 0.05 was considered significant. During the study period, we identified 99 IUGR twins meeting our inclusion criteria. These were matched with 396 singletons with IUGR. The mean gestational age at delivery for the twins was 34 ± 3.8 weeks and 35 ± 3.5 weeks for the singletons (p = 0.11). The PMR in twins was significantly higher than in singletons (OR, 2.2; 95% confidence interval, 1.1 to 5.7). Perinatal morbidity was similarly significantly higher in IUGR twins. Compared with age-matched singletons, twins with IUGR have higher perinatal mortality and morbidity rates.

Original languageEnglish (US)
Pages (from-to)269-273
Number of pages5
JournalAmerican Journal of Perinatology
Volume22
Issue number5
DOIs
StatePublished - Jul 1 2005

Fingerprint

Fetal Growth Retardation
Growth
Perinatal Mortality
Neonatal Intensive Care Units
Gestational Age
Periventricular Leukomalacia
Morbidity
Necrotizing Enterocolitis
Cohort Studies
Research Design
Retrospective Studies
Databases
Confidence Intervals
Hemorrhage

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Odibo, Anthony O. ; McDonald, Raegan E. ; Stamilio, David M. ; Ural, Serdar H. ; Macones, George A. / Perinatal outcomes in growth-restricted twins compared with age-matched growth-restricted singletons. In: American Journal of Perinatology. 2005 ; Vol. 22, No. 5. pp. 269-273.
@article{1d536cedb73c4fa4bcf225a8e3fca642,
title = "Perinatal outcomes in growth-restricted twins compared with age-matched growth-restricted singletons",
abstract = "The objective of this study was to compare the perinatal outcomes in growth-restricted (IUGR) twins with a matched group of IUGR singletons. We performed a retrospective cohort study evaluating the perinatal outcomes in IUGR twins matched for gestational age at delivery to the next four IUGR singletons (1:4) in our perinatal database. The perinatal outcomes evaluated included rates of uncorrected perinatal mortality (PMR), admission to the neonatal intensive care unit (NICU), respiratory distress syndrome, grades 3 or 4 intraventricular hemorrhage, necrotizing enterocolitis, periventricular leukomalacia, and length of NICU stay. A cohort of twins with IUGR were matched with a cohort of IUGR singletons and compared for perinatal outcomes. A p value < 0.05 was considered significant. During the study period, we identified 99 IUGR twins meeting our inclusion criteria. These were matched with 396 singletons with IUGR. The mean gestational age at delivery for the twins was 34 ± 3.8 weeks and 35 ± 3.5 weeks for the singletons (p = 0.11). The PMR in twins was significantly higher than in singletons (OR, 2.2; 95{\%} confidence interval, 1.1 to 5.7). Perinatal morbidity was similarly significantly higher in IUGR twins. Compared with age-matched singletons, twins with IUGR have higher perinatal mortality and morbidity rates.",
author = "Odibo, {Anthony O.} and McDonald, {Raegan E.} and Stamilio, {David M.} and Ural, {Serdar H.} and Macones, {George A.}",
year = "2005",
month = "7",
day = "1",
doi = "10.1055/s-2005-870657",
language = "English (US)",
volume = "22",
pages = "269--273",
journal = "American Journal of Perinatology",
issn = "0735-1631",
publisher = "Thieme Medical Publishers",
number = "5",

}

Perinatal outcomes in growth-restricted twins compared with age-matched growth-restricted singletons. / Odibo, Anthony O.; McDonald, Raegan E.; Stamilio, David M.; Ural, Serdar H.; Macones, George A.

In: American Journal of Perinatology, Vol. 22, No. 5, 01.07.2005, p. 269-273.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Perinatal outcomes in growth-restricted twins compared with age-matched growth-restricted singletons

AU - Odibo, Anthony O.

AU - McDonald, Raegan E.

AU - Stamilio, David M.

AU - Ural, Serdar H.

AU - Macones, George A.

PY - 2005/7/1

Y1 - 2005/7/1

N2 - The objective of this study was to compare the perinatal outcomes in growth-restricted (IUGR) twins with a matched group of IUGR singletons. We performed a retrospective cohort study evaluating the perinatal outcomes in IUGR twins matched for gestational age at delivery to the next four IUGR singletons (1:4) in our perinatal database. The perinatal outcomes evaluated included rates of uncorrected perinatal mortality (PMR), admission to the neonatal intensive care unit (NICU), respiratory distress syndrome, grades 3 or 4 intraventricular hemorrhage, necrotizing enterocolitis, periventricular leukomalacia, and length of NICU stay. A cohort of twins with IUGR were matched with a cohort of IUGR singletons and compared for perinatal outcomes. A p value < 0.05 was considered significant. During the study period, we identified 99 IUGR twins meeting our inclusion criteria. These were matched with 396 singletons with IUGR. The mean gestational age at delivery for the twins was 34 ± 3.8 weeks and 35 ± 3.5 weeks for the singletons (p = 0.11). The PMR in twins was significantly higher than in singletons (OR, 2.2; 95% confidence interval, 1.1 to 5.7). Perinatal morbidity was similarly significantly higher in IUGR twins. Compared with age-matched singletons, twins with IUGR have higher perinatal mortality and morbidity rates.

AB - The objective of this study was to compare the perinatal outcomes in growth-restricted (IUGR) twins with a matched group of IUGR singletons. We performed a retrospective cohort study evaluating the perinatal outcomes in IUGR twins matched for gestational age at delivery to the next four IUGR singletons (1:4) in our perinatal database. The perinatal outcomes evaluated included rates of uncorrected perinatal mortality (PMR), admission to the neonatal intensive care unit (NICU), respiratory distress syndrome, grades 3 or 4 intraventricular hemorrhage, necrotizing enterocolitis, periventricular leukomalacia, and length of NICU stay. A cohort of twins with IUGR were matched with a cohort of IUGR singletons and compared for perinatal outcomes. A p value < 0.05 was considered significant. During the study period, we identified 99 IUGR twins meeting our inclusion criteria. These were matched with 396 singletons with IUGR. The mean gestational age at delivery for the twins was 34 ± 3.8 weeks and 35 ± 3.5 weeks for the singletons (p = 0.11). The PMR in twins was significantly higher than in singletons (OR, 2.2; 95% confidence interval, 1.1 to 5.7). Perinatal morbidity was similarly significantly higher in IUGR twins. Compared with age-matched singletons, twins with IUGR have higher perinatal mortality and morbidity rates.

UR - http://www.scopus.com/inward/record.url?scp=23244442454&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=23244442454&partnerID=8YFLogxK

U2 - 10.1055/s-2005-870657

DO - 10.1055/s-2005-870657

M3 - Article

C2 - 16041638

AN - SCOPUS:23244442454

VL - 22

SP - 269

EP - 273

JO - American Journal of Perinatology

JF - American Journal of Perinatology

SN - 0735-1631

IS - 5

ER -