42 Citations (Scopus)

Abstract

1. The effects of frequency of orthodromic and antidromic stimulation of CA3 on formation of electrographic seizurelike discharges in CA1 was studied in the high potassium hippocampal slice. 2. Within the range of stimulation of CA3 used, 0.1-10.0 Hz, a narrow range was identified between 1.0 and 1.3 Hz, where the tonic phase of seizure generation in CA1 was suppressed. This suppression was observed for both Schaffer collateral and mossy fiber stimulation.

Original languageEnglish (US)
Pages (from-to)876-879
Number of pages4
JournalJournal of Neurophysiology
Volume73
Issue number2
DOIs
StatePublished - Jan 1 1995

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Hippocampus
Potassium
Seizures
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Physiology

Cite this

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title = "Periodic pacing an in vitro epileptic focus",
abstract = "1. The effects of frequency of orthodromic and antidromic stimulation of CA3 on formation of electrographic seizurelike discharges in CA1 was studied in the high potassium hippocampal slice. 2. Within the range of stimulation of CA3 used, 0.1-10.0 Hz, a narrow range was identified between 1.0 and 1.3 Hz, where the tonic phase of seizure generation in CA1 was suppressed. This suppression was observed for both Schaffer collateral and mossy fiber stimulation.",
author = "K. Jerger and Steven Schiff",
year = "1995",
month = "1",
day = "1",
doi = "10.1152/jn.1995.73.2.876",
language = "English (US)",
volume = "73",
pages = "876--879",
journal = "Journal of Neurophysiology",
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publisher = "American Physiological Society",
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}

Periodic pacing an in vitro epileptic focus. / Jerger, K.; Schiff, Steven.

In: Journal of Neurophysiology, Vol. 73, No. 2, 01.01.1995, p. 876-879.

Research output: Contribution to journalArticle

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T1 - Periodic pacing an in vitro epileptic focus

AU - Jerger, K.

AU - Schiff, Steven

PY - 1995/1/1

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N2 - 1. The effects of frequency of orthodromic and antidromic stimulation of CA3 on formation of electrographic seizurelike discharges in CA1 was studied in the high potassium hippocampal slice. 2. Within the range of stimulation of CA3 used, 0.1-10.0 Hz, a narrow range was identified between 1.0 and 1.3 Hz, where the tonic phase of seizure generation in CA1 was suppressed. This suppression was observed for both Schaffer collateral and mossy fiber stimulation.

AB - 1. The effects of frequency of orthodromic and antidromic stimulation of CA3 on formation of electrographic seizurelike discharges in CA1 was studied in the high potassium hippocampal slice. 2. Within the range of stimulation of CA3 used, 0.1-10.0 Hz, a narrow range was identified between 1.0 and 1.3 Hz, where the tonic phase of seizure generation in CA1 was suppressed. This suppression was observed for both Schaffer collateral and mossy fiber stimulation.

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U2 - 10.1152/jn.1995.73.2.876

DO - 10.1152/jn.1995.73.2.876

M3 - Article

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EP - 879

JO - Journal of Neurophysiology

JF - Journal of Neurophysiology

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