Perioperative Anesthetic Management of Patients Having Liver Transplantation for Uncommon Conditions

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

This review focuses on the perioperative anesthetic management of patients having liver transplantation (LT) performed for several uncommon indications or in combination with rare pathology. Conditions discussed in the article include Alagille syndrome, hypertrophic cardiomyopathy, Gilbert’s syndrome, porphyria, Wilson’s disease, and Budd-Chiari syndrome. In comparison to other indications, LT in these settings is infrequent because of the low incidence of these pathologies. Most of these conditions (with the exception of Gilbert syndrome) are associated with a high probability of significant perioperative complications and increased mortality and morbidity. Experience in management of these unusual conditions is only gained over time. Developing clinical pathways for patients with these conditions should result in outcomes similar to LT performed for more common indications.

Original languageEnglish (US)
Pages (from-to)197-210
Number of pages14
JournalSeminars in Cardiothoracic and Vascular Anesthesia
Volume22
Issue number2
DOIs
StatePublished - Jun 1 2018

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Gilbert Disease
Liver Transplantation
Anesthetics
Alagille Syndrome
Pathology
Budd-Chiari Syndrome
Porphyrias
Hepatolenticular Degeneration
Critical Pathways
Hypertrophic Cardiomyopathy
Morbidity
Mortality
Incidence

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Anesthesiology and Pain Medicine

Cite this

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title = "Perioperative Anesthetic Management of Patients Having Liver Transplantation for Uncommon Conditions",
abstract = "This review focuses on the perioperative anesthetic management of patients having liver transplantation (LT) performed for several uncommon indications or in combination with rare pathology. Conditions discussed in the article include Alagille syndrome, hypertrophic cardiomyopathy, Gilbert’s syndrome, porphyria, Wilson’s disease, and Budd-Chiari syndrome. In comparison to other indications, LT in these settings is infrequent because of the low incidence of these pathologies. Most of these conditions (with the exception of Gilbert syndrome) are associated with a high probability of significant perioperative complications and increased mortality and morbidity. Experience in management of these unusual conditions is only gained over time. Developing clinical pathways for patients with these conditions should result in outcomes similar to LT performed for more common indications.",
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