Peritrophic Envelope as a Functional Antioxidant

Clinton B. Summers, Gary Felton

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

The peritrophic envelope has long been considered an important microbial barrier to midgut infection and as a selective filter for the exclusion of dietary toxins. In this paper, we present data indicating that the peritrophic envelope (PE) of Helicoverpa zea serves as a functional antioxidant, protecting the midgut epithelium from damage by dietary prooxidants. Results from in vitro assays indicate that PE effectively scavenges hydroxyl radicals and reduces hydroperoxide formation in isolated midgut tissues exposed to model free radical generating systems. The extraordinary similarity in location and function of the PE to gastric mucins of vertebrates is discussed.

Original languageEnglish (US)
Pages (from-to)131-142
Number of pages12
JournalArchives of Insect Biochemistry and Physiology
Volume32
Issue number1
DOIs
StatePublished - Jan 1 1996

All Science Journal Classification (ASJC) codes

  • Physiology
  • Biochemistry
  • Insect Science

Fingerprint Dive into the research topics of 'Peritrophic Envelope as a Functional Antioxidant'. Together they form a unique fingerprint.

  • Cite this