Injectable micron-sized polymeric particles were prepared and used as carriers of radiolabels and drugs for diagnosis and radiotherapy. Monosize polyethylcyanoacrylate (PECA) microspheres were prepared by phase inversion polymerization. Polylactide and polylactide/polyethyleneglycol (PLA/PEG) particles were obtained by solvent evaporation. Albumin and fibronectin were also physically adsorbed on these particles. Phagocytosis of these particles using fresh human blood, and homogeneous mouse peritoneal and lung macrophage suspensions was evaluated. The results were evaluated by phase-contrast microscopy.
|Original language||English (US)|
|Journal||Artificial Cells, Blood Substitutes, and Immobilization Biotechnology|
|State||Published - Nov 1994|
All Science Journal Classification (ASJC) codes
- Biomedical Engineering