Pharmacologic Management for Heart Failure and Emerging Therapies

Diana H. Kim, Feng Ju Chien, Howard J. Eisen

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Purpose of Review: This review aims to summarize the growing body of literature of HF with reduced ejection fraction (HFrEF) and preserved ejection fraction (HFpEF) with a focus on recent pharmacologics. Recent Findings: HFrEF continues to be more widely investigated than HFpEF. Ivabradine and combinatorial treatment with sacubitril and valsartan are promising newly approved therapies. Other experimental therapies have emerged, which include Serelaxin, Empagliflozin, Neuregulin, and Omecamtive mecarbil, among others. These drugs need to continue to be investigated for safety and efficacy. Summary: We predict ivabradine and combinatorial treatment with sacubitril-valsartan to develop as a widespread therapy. New therapies should be aimed at treating HFpEF or target the cardiomyocyte itself.

Original languageEnglish (US)
Article number94
JournalCurrent Cardiology Reports
Volume19
Issue number10
DOIs
StatePublished - Oct 1 2017

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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