Pharmacology of medications used for ovarian stimulation

Alexander M. Quaas, Richard S. Legro

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Medications to stimulate the ovaries may be used to induce ovulation in patients with anovulatory infertility or to hyperstimulate the ovaries in a controlled fashion in ovulatory patients as part of assisted reproductive treatments (ART). The pharmacology of all current major medications used to stimulate ovarian function is reviewed in this article, including letrozole, clomiphene citrate, gonadotropins, and pulsatile gonadotropin releasing hormone (GnRH). Novel potential compounds and adjuvant treatment approaches are also discussed, such as kisspeptin agonists and androgens.

Original languageEnglish (US)
Pages (from-to)21-33
Number of pages13
JournalBest Practice and Research: Clinical Endocrinology and Metabolism
Issue number1
StatePublished - Feb 2019

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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