Pharmacology of medications used for ovarian stimulation

Alexander M. Quaas, Richard Legro

Research output: Contribution to journalReview article

Abstract

Medications to stimulate the ovaries may be used to induce ovulation in patients with anovulatory infertility or to hyperstimulate the ovaries in a controlled fashion in ovulatory patients as part of assisted reproductive treatments (ART). The pharmacology of all current major medications used to stimulate ovarian function is reviewed in this article, including letrozole, clomiphene citrate, gonadotropins, and pulsatile gonadotropin releasing hormone (GnRH). Novel potential compounds and adjuvant treatment approaches are also discussed, such as kisspeptin agonists and androgens.

Original languageEnglish (US)
Pages (from-to)21-33
Number of pages13
JournalBest Practice and Research: Clinical Endocrinology and Metabolism
Volume33
Issue number1
DOIs
StatePublished - Feb 1 2019

Fingerprint

letrozole
Ovulation Induction
Ovary
Kisspeptins
Pharmacology
Clomiphene
Ovulation
Gonadotropins
Gonadotropin-Releasing Hormone
Infertility
Androgens
Therapeutics

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

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Pharmacology of medications used for ovarian stimulation. / Quaas, Alexander M.; Legro, Richard.

In: Best Practice and Research: Clinical Endocrinology and Metabolism, Vol. 33, No. 1, 01.02.2019, p. 21-33.

Research output: Contribution to journalReview article

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