Pheromonotropic activity of naturally occurring pyrokinin insect neuropeptides (FXPRLamide) in Helicoverpa zea

Rella L. Abernathy, Ronald J. Nachman, Peter E.A. Teal, Okitsugu Yamashita, James Homer Tumlinson, III

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Insect neuropeptides, having the common C-terminal sequence FXPRLamide (X = V, T, S, or G), were tested for pheromonotropic activity in the moth, Helicoverpa zea. Dose-response studies indicated that locustamyotropin-II or locustapyrokinin-II induced production of more pheromone than was stimulated by the pheromone biosynthesis activating neuropeptide of this moth. Other peptides showed various degrees of pheromonotropic activity. The data indicated that substitution of the variable amino acid in the C-terminal pentapeptide sequence resulted in significant differences in pheromonotropic activity. However, the overall structure of the peptide was also found to be of importance.

Original languageEnglish (US)
Pages (from-to)215-219
Number of pages5
JournalPeptides
Volume16
Issue number2
DOIs
StatePublished - Jan 1 1995

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Moths
Pheromones
Neuropeptides
Zea mays
Insects
Peptides
Biosynthesis
Amino Acid Substitution
Substitution reactions
Amino Acids
pyrokinin
locustapyrokinin II
locustamyotropin

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physiology
  • Endocrinology
  • Cellular and Molecular Neuroscience

Cite this

Abernathy, Rella L. ; Nachman, Ronald J. ; Teal, Peter E.A. ; Yamashita, Okitsugu ; Tumlinson, III, James Homer. / Pheromonotropic activity of naturally occurring pyrokinin insect neuropeptides (FXPRLamide) in Helicoverpa zea. In: Peptides. 1995 ; Vol. 16, No. 2. pp. 215-219.
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Pheromonotropic activity of naturally occurring pyrokinin insect neuropeptides (FXPRLamide) in Helicoverpa zea. / Abernathy, Rella L.; Nachman, Ronald J.; Teal, Peter E.A.; Yamashita, Okitsugu; Tumlinson, III, James Homer.

In: Peptides, Vol. 16, No. 2, 01.01.1995, p. 215-219.

Research output: Contribution to journalArticle

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