Phylogenetic analysis and subtyping of acute and fulminant strains of hepatitis E virus isolates of North India with reference to disease severity

Sujit Kumar Pujhari, Subrat Kumar, Radha Kanta Ratho, Yogesh Kumar Chawla, Anuradha Chakraborti

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Hepatitis E is endemic to the Indian subcontinent, with a seroprevalence of 4-20%, and more than 25% of acute viral hepatitis is due to HEV. The northern parts of India have been experiencing outbreaks and sporadic cases of HEV since 1955. In a total of sixteen HEV sequences, ten acute viral hepatitis and 6 fulminant hepatic failure cases were analysed. Subtypes 1a and 1c of HEV are prevalent in North India, with the subtype-1c showing a trend towards fulminancy.

Original languageEnglish (US)
Pages (from-to)1483-1486
Number of pages4
JournalArchives of Virology
Volume155
Issue number9
DOIs
StatePublished - Jun 18 2010

All Science Journal Classification (ASJC) codes

  • Virology

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