Phylogenetic analysis of non-O157 Shiga toxin-producing Escherichia coli strains by whole-genome sequencing

Wenting Ju, Guojie Cao, Lydia Rump, Errol Strain, Yan Luo, Ruth Timme, Marc Allard, Shaohua Zhao, Eric Brown, Jianghong Meng

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

Non-O157 Shiga toxin-producing Escherichia coli (STEC) strains are emerging food-borne pathogens causing life-threatening diseases and food-borne outbreaks. A better understanding of their evolution provides a framework for developing tools to control food safety. We obtained 15 genomes of non-O157 STEC strains, including O26, O111, and O103 strains. Phylogenetic trees revealed a close relationship between O26:H11 and O111:H11 and a scattered distribution of O111. We hypothesize that STEC serotypes with the same H antigens might share common ancestors.

Original languageEnglish (US)
Pages (from-to)4123-4127
Number of pages5
JournalJournal of clinical microbiology
Volume50
Issue number12
DOIs
StatePublished - Dec 1 2012

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

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    Ju, W., Cao, G., Rump, L., Strain, E., Luo, Y., Timme, R., Allard, M., Zhao, S., Brown, E., & Meng, J. (2012). Phylogenetic analysis of non-O157 Shiga toxin-producing Escherichia coli strains by whole-genome sequencing. Journal of clinical microbiology, 50(12), 4123-4127. https://doi.org/10.1128/JCM.02262-12