Physiologic and structural indices of vascular function in paraplegics

Jeffrey S. Shenberger, Gretchen J. Leaman, Marsha M. Neumyer, Timothy I. Musch, Lawrence Sinoway

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

In an effort to determine whether chronic physical forearm activity would increase both structural and physiologic indices of peripheral forearm vasodilation, we studied a group (N = 7) of individuals chronically performing high levels of arm work, young wheelchair-confined paraplegics, and compared them with ten young, able bodied control subjects. The index of vasodilator capacity was the flow response following the release of 10 min of arterial occlusion, the peak reactive hyperemic blood flow response (RHBF). The index of a structural effect of training on the vasculature was the brachial artery diameter (cm) derived by simultaneous measurement of velocity and forearm blood flow (area = flow·forearm volume·velocity-1) Vascular function differed significantly between the groups, with a greater RHBF (paraplegics, 53.8 ± 3.7; controls, 38.2± 1.5 ml.min-1-100 ml-1; P < 0.05)andalarger brachial artery diameter at rest (paraplegics, 0.4 ± 0.01 vs controls, 0.3 ± 0.02 cm; P < 0.05) in the paraplegics. We conclude that chronic upper extremity activity leads to an enhanced capability to vasodilate resistance vessels acutely and to a structural dilation of large conductance vessels.

Original languageEnglish (US)
Pages (from-to)96-101
Number of pages6
JournalMedicine and Science in Sports and Exercise
Volume22
Issue number1
StatePublished - Jan 1 1990

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Forearm
Blood Vessels
Brachial Artery
Wheelchairs
Blood Flow Velocity
Vasodilator Agents
Vasodilation
Upper Extremity
Dilatation
Arm

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Shenberger, J. S., Leaman, G. J., Neumyer, M. M., Musch, T. I., & Sinoway, L. (1990). Physiologic and structural indices of vascular function in paraplegics. Medicine and Science in Sports and Exercise, 22(1), 96-101.
Shenberger, Jeffrey S. ; Leaman, Gretchen J. ; Neumyer, Marsha M. ; Musch, Timothy I. ; Sinoway, Lawrence. / Physiologic and structural indices of vascular function in paraplegics. In: Medicine and Science in Sports and Exercise. 1990 ; Vol. 22, No. 1. pp. 96-101.
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Shenberger, JS, Leaman, GJ, Neumyer, MM, Musch, TI & Sinoway, L 1990, 'Physiologic and structural indices of vascular function in paraplegics', Medicine and Science in Sports and Exercise, vol. 22, no. 1, pp. 96-101.

Physiologic and structural indices of vascular function in paraplegics. / Shenberger, Jeffrey S.; Leaman, Gretchen J.; Neumyer, Marsha M.; Musch, Timothy I.; Sinoway, Lawrence.

In: Medicine and Science in Sports and Exercise, Vol. 22, No. 1, 01.01.1990, p. 96-101.

Research output: Contribution to journalArticle

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