Physiological characteristics and mycotoxins of human clinical isolates of Fusarium species

Yoshitsugu Sugiura, John R. Barr, Dana B. Barr, John W. Brock, Cheryl M. Elie, Yoshio Ueno, Donald G. Patterson, Morris E. Potter, Errol Reiss

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Thirty-three strains of Fusarium species from clinical sources including F. solani, F. oxysporum, F. moniliforme, F. proliferatum, F. subglutinans and F. chlamydosporum were examined for their physiological characteristics and mycotoxin production. Of this collection 29 exhibited growth at 37 °C and 21 were resistant to cycloheximide. Two strains of F. moniliforme and two strains of F. proliferatum produced fumonisins. No strains in this collection produced detectable amounts of trichothecenes. All 18 strains of F. solani tested produced the immunosuppressive agent cyclosporin A. The cyclosporin A producing ability of clinical isolates of F. solani may influence their pathogenic potential.

Original languageEnglish (US)
Pages (from-to)1462-1468
Number of pages7
JournalMycological Research
Volume103
Issue number11
DOIs
StatePublished - Nov 1999

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Plant Science

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