Physiology of tmRNA: what gets tagged and why?

Research output: Contribution to journalReview articlepeer-review

38 Scopus citations

Abstract

Transfer-messenger RNA (tmRNA) enters stalled translational complexes and, with small protein B (SmpB), mediates peptide tagging of the nascent protein and release of the stalled ribosome. Recent studies clarify how the tmRNA system is targeted to ribosomes and suggest that tmRNA-tagging is used for both quality control and specific regulation of cellular physiology.

Original languageEnglish (US)
Pages (from-to)169-175
Number of pages7
JournalCurrent Opinion in Microbiology
Volume10
Issue number2
DOIs
StatePublished - Apr 2007

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases

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