Pilomyxoid astrocytoma: A review CME

Ricardo J. Komotar, J. Mocco, Benjamin S. Carson, Michael E. Sughrue, Brad Zacharia, Alexander C. Sisti, Peter D. Canoll, Alexander G. Khandji, Tarik Tihan, Peter C. Burger, Jeffrey N. Bruce, Charles Vega

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

Pilomyxoid astrocytoma (PMA) is a recently described type of brain tumor. PMA shares similar features with pilocytic astrocytoma (PA), the most common central nervous system (CNS) tumor in the pediatric population, yet displays subtle histologic differences. Previous studies have shown PMA to behave more aggressively than PA, with shorter progression-free and overall survival as well as a higher rate of recurrence and CNS dissemination. These findings suggest that PMA may be a unique and distinct neoplasm. This review summarizes the histologic, clinical, and radiographic characteristics of PMA. In addition, the current treatment options and research endeavors involving this disease are described. Increased recognition of PMA within the medical community has the potential to affect the treatment and prognosis of pediatric low-grade astrocytomas.

Original languageEnglish (US)
JournalMedGenMed Medscape General Medicine
Volume6
Issue number4
StatePublished - Dec 1 2004

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Astrocytoma
Pediatrics
Central Nervous System Neoplasms
Brain Neoplasms
Disease-Free Survival
Central Nervous System
Recurrence

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Komotar, R. J., Mocco, J., Carson, B. S., Sughrue, M. E., Zacharia, B., Sisti, A. C., ... Vega, C. (2004). Pilomyxoid astrocytoma: A review CME. MedGenMed Medscape General Medicine, 6(4).
Komotar, Ricardo J. ; Mocco, J. ; Carson, Benjamin S. ; Sughrue, Michael E. ; Zacharia, Brad ; Sisti, Alexander C. ; Canoll, Peter D. ; Khandji, Alexander G. ; Tihan, Tarik ; Burger, Peter C. ; Bruce, Jeffrey N. ; Vega, Charles. / Pilomyxoid astrocytoma : A review CME. In: MedGenMed Medscape General Medicine. 2004 ; Vol. 6, No. 4.
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Komotar, RJ, Mocco, J, Carson, BS, Sughrue, ME, Zacharia, B, Sisti, AC, Canoll, PD, Khandji, AG, Tihan, T, Burger, PC, Bruce, JN & Vega, C 2004, 'Pilomyxoid astrocytoma: A review CME', MedGenMed Medscape General Medicine, vol. 6, no. 4.

Pilomyxoid astrocytoma : A review CME. / Komotar, Ricardo J.; Mocco, J.; Carson, Benjamin S.; Sughrue, Michael E.; Zacharia, Brad; Sisti, Alexander C.; Canoll, Peter D.; Khandji, Alexander G.; Tihan, Tarik; Burger, Peter C.; Bruce, Jeffrey N.; Vega, Charles.

In: MedGenMed Medscape General Medicine, Vol. 6, No. 4, 01.12.2004.

Research output: Contribution to journalReview article

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T2 - A review CME

AU - Komotar, Ricardo J.

AU - Mocco, J.

AU - Carson, Benjamin S.

AU - Sughrue, Michael E.

AU - Zacharia, Brad

AU - Sisti, Alexander C.

AU - Canoll, Peter D.

AU - Khandji, Alexander G.

AU - Tihan, Tarik

AU - Burger, Peter C.

AU - Bruce, Jeffrey N.

AU - Vega, Charles

PY - 2004/12/1

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Komotar RJ, Mocco J, Carson BS, Sughrue ME, Zacharia B, Sisti AC et al. Pilomyxoid astrocytoma: A review CME. MedGenMed Medscape General Medicine. 2004 Dec 1;6(4).