Plant single-cell and single-cell-type metabolomics

Biswapriya B. Misra, Sarah Mary Assmann, Sixue Chen

Research output: Contribution to journalReview article

48 Citations (Scopus)

Abstract

In conjunction with genomics, transcriptomics, and proteomics, plant metabolomics is providing large data sets that are paving the way towards a comprehensive and holistic understanding of plant growth, development, defense, and productivity. However, dilution effects from organ- and tissue-based sampling of metabolomes have limited our understanding of the intricate regulation of metabolic pathways and networks at the cellular level. Recent advances in metabolomics methodologies, along with the post-genomic expansion of bioinformatics knowledge and functional genomics tools, have allowed the gathering of enriched information on individual cells and single cell types. Here we review progress, current status, opportunities, and challenges presented by single cell-based metabolomics research in plants.

Original languageEnglish (US)
Pages (from-to)637-646
Number of pages10
JournalTrends in Plant Science
Volume19
Issue number10
DOIs
StatePublished - Oct 1 2014

Fingerprint

metabolomics
genomics
metabolome
cells
transcriptomics
bioinformatics
proteomics
biochemical pathways
plant growth
sampling
methodology

All Science Journal Classification (ASJC) codes

  • Plant Science

Cite this

Misra, Biswapriya B. ; Assmann, Sarah Mary ; Chen, Sixue. / Plant single-cell and single-cell-type metabolomics. In: Trends in Plant Science. 2014 ; Vol. 19, No. 10. pp. 637-646.
@article{ee09beaa280e4a008ec6e224b9df4b79,
title = "Plant single-cell and single-cell-type metabolomics",
abstract = "In conjunction with genomics, transcriptomics, and proteomics, plant metabolomics is providing large data sets that are paving the way towards a comprehensive and holistic understanding of plant growth, development, defense, and productivity. However, dilution effects from organ- and tissue-based sampling of metabolomes have limited our understanding of the intricate regulation of metabolic pathways and networks at the cellular level. Recent advances in metabolomics methodologies, along with the post-genomic expansion of bioinformatics knowledge and functional genomics tools, have allowed the gathering of enriched information on individual cells and single cell types. Here we review progress, current status, opportunities, and challenges presented by single cell-based metabolomics research in plants.",
author = "Misra, {Biswapriya B.} and Assmann, {Sarah Mary} and Sixue Chen",
year = "2014",
month = "10",
day = "1",
doi = "10.1016/j.tplants.2014.05.005",
language = "English (US)",
volume = "19",
pages = "637--646",
journal = "Trends in Plant Science",
issn = "1360-1385",
publisher = "Elsevier Limited",
number = "10",

}

Plant single-cell and single-cell-type metabolomics. / Misra, Biswapriya B.; Assmann, Sarah Mary; Chen, Sixue.

In: Trends in Plant Science, Vol. 19, No. 10, 01.10.2014, p. 637-646.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Plant single-cell and single-cell-type metabolomics

AU - Misra, Biswapriya B.

AU - Assmann, Sarah Mary

AU - Chen, Sixue

PY - 2014/10/1

Y1 - 2014/10/1

N2 - In conjunction with genomics, transcriptomics, and proteomics, plant metabolomics is providing large data sets that are paving the way towards a comprehensive and holistic understanding of plant growth, development, defense, and productivity. However, dilution effects from organ- and tissue-based sampling of metabolomes have limited our understanding of the intricate regulation of metabolic pathways and networks at the cellular level. Recent advances in metabolomics methodologies, along with the post-genomic expansion of bioinformatics knowledge and functional genomics tools, have allowed the gathering of enriched information on individual cells and single cell types. Here we review progress, current status, opportunities, and challenges presented by single cell-based metabolomics research in plants.

AB - In conjunction with genomics, transcriptomics, and proteomics, plant metabolomics is providing large data sets that are paving the way towards a comprehensive and holistic understanding of plant growth, development, defense, and productivity. However, dilution effects from organ- and tissue-based sampling of metabolomes have limited our understanding of the intricate regulation of metabolic pathways and networks at the cellular level. Recent advances in metabolomics methodologies, along with the post-genomic expansion of bioinformatics knowledge and functional genomics tools, have allowed the gathering of enriched information on individual cells and single cell types. Here we review progress, current status, opportunities, and challenges presented by single cell-based metabolomics research in plants.

UR - http://www.scopus.com/inward/record.url?scp=84908204987&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84908204987&partnerID=8YFLogxK

U2 - 10.1016/j.tplants.2014.05.005

DO - 10.1016/j.tplants.2014.05.005

M3 - Review article

VL - 19

SP - 637

EP - 646

JO - Trends in Plant Science

JF - Trends in Plant Science

SN - 1360-1385

IS - 10

ER -