Plasma lipid changes in young adult couples consuming polyunsaturated meats and dairy products

R. E. Hodges, A. F. Salel, W. L. Dunkley, Robert Zelis, P. F. McDonagh, C. Clifford, R. K. Hobbs, L. M. Smith, A. Fan, D. T. Mason, C. Lykke

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

25 Young couples consumed either a saturated or polyunsaturated fat diet for a 20 wk period. The polyunsaturated beef, lamb, and dried products, high in linoleic acid, were produced by feeding ruminant animals 'protected lipid' feeds which prevent hydrogenation of fats in the rumen. The experimental design provided for 4 dietary groups: A) saturated diet for 20 wk; B) polyunsaturated diet for 20 wk; C) saturated diet for 10 wk then polyunsaturated diet for 10 wk; and D) polyunsaturated for 10 wk and then saturated diet for 10 wk. Polyunsaturated to saturated ratios (linoleic: total saturated fatty acids) for the diets were: prestudy, 0.43-0.56; saturated, 0.11-0.14; polyunsaturated, 0.56-0.62. Factors other than diet that appeared to affect cholesterol responses were carefully considered. During the initial 3 wk (regimentation period) plasma cholesterol concentrations decreased in all groups irrespective of diet. This was followed by 2 experimental periods in which the effects of the prescribed diets were readily apparent (response periods I and II). The final 4 wk of the study were characterized by diminishing compliance with the dietary discipline (abatement period). Subjects in each group (A,B,C,D) were subdivided into high and low on a basis of each group's initial median cholesterol level. Those in the high subgroups were very responsive to dietary changes whereas those in the low subgroups were not. Combined responses of high subjects were: polyunsaturated diet -10.7 mg/dl (P < 0.025), saturated diet, + 7.8 mg/dl (P < 0.05). Combined difference between saturated and polyunsaturated diets was 18.5 mg/dl or approximately a 10% cholesterol difference between the experimental polyunsaturated and saturated diets.

Original languageEnglish (US)
Pages (from-to)1126-1140
Number of pages15
JournalAmerican Journal of Clinical Nutrition
Volume28
Issue number10
StatePublished - Dec 1 1975

Fingerprint

Meat Products
Dairy Products
young adults
meat products
blood lipids
dairy products
Young Adult
Diet
Lipids
diet
Cholesterol
cholesterol
Fats
Hydrogenation
hydrogenation
animal feeding
Rumen
Ruminants
Linoleic Acid
lipids

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Food Science

Cite this

Hodges, R. E., Salel, A. F., Dunkley, W. L., Zelis, R., McDonagh, P. F., Clifford, C., ... Lykke, C. (1975). Plasma lipid changes in young adult couples consuming polyunsaturated meats and dairy products. American Journal of Clinical Nutrition, 28(10), 1126-1140.
Hodges, R. E. ; Salel, A. F. ; Dunkley, W. L. ; Zelis, Robert ; McDonagh, P. F. ; Clifford, C. ; Hobbs, R. K. ; Smith, L. M. ; Fan, A. ; Mason, D. T. ; Lykke, C. / Plasma lipid changes in young adult couples consuming polyunsaturated meats and dairy products. In: American Journal of Clinical Nutrition. 1975 ; Vol. 28, No. 10. pp. 1126-1140.
@article{06ddaa9496d54142a04a2700a2366506,
title = "Plasma lipid changes in young adult couples consuming polyunsaturated meats and dairy products",
abstract = "25 Young couples consumed either a saturated or polyunsaturated fat diet for a 20 wk period. The polyunsaturated beef, lamb, and dried products, high in linoleic acid, were produced by feeding ruminant animals 'protected lipid' feeds which prevent hydrogenation of fats in the rumen. The experimental design provided for 4 dietary groups: A) saturated diet for 20 wk; B) polyunsaturated diet for 20 wk; C) saturated diet for 10 wk then polyunsaturated diet for 10 wk; and D) polyunsaturated for 10 wk and then saturated diet for 10 wk. Polyunsaturated to saturated ratios (linoleic: total saturated fatty acids) for the diets were: prestudy, 0.43-0.56; saturated, 0.11-0.14; polyunsaturated, 0.56-0.62. Factors other than diet that appeared to affect cholesterol responses were carefully considered. During the initial 3 wk (regimentation period) plasma cholesterol concentrations decreased in all groups irrespective of diet. This was followed by 2 experimental periods in which the effects of the prescribed diets were readily apparent (response periods I and II). The final 4 wk of the study were characterized by diminishing compliance with the dietary discipline (abatement period). Subjects in each group (A,B,C,D) were subdivided into high and low on a basis of each group's initial median cholesterol level. Those in the high subgroups were very responsive to dietary changes whereas those in the low subgroups were not. Combined responses of high subjects were: polyunsaturated diet -10.7 mg/dl (P < 0.025), saturated diet, + 7.8 mg/dl (P < 0.05). Combined difference between saturated and polyunsaturated diets was 18.5 mg/dl or approximately a 10{\%} cholesterol difference between the experimental polyunsaturated and saturated diets.",
author = "Hodges, {R. E.} and Salel, {A. F.} and Dunkley, {W. L.} and Robert Zelis and McDonagh, {P. F.} and C. Clifford and Hobbs, {R. K.} and Smith, {L. M.} and A. Fan and Mason, {D. T.} and C. Lykke",
year = "1975",
month = "12",
day = "1",
language = "English (US)",
volume = "28",
pages = "1126--1140",
journal = "American Journal of Clinical Nutrition",
issn = "0002-9165",
publisher = "American Society for Nutrition",
number = "10",

}

Hodges, RE, Salel, AF, Dunkley, WL, Zelis, R, McDonagh, PF, Clifford, C, Hobbs, RK, Smith, LM, Fan, A, Mason, DT & Lykke, C 1975, 'Plasma lipid changes in young adult couples consuming polyunsaturated meats and dairy products', American Journal of Clinical Nutrition, vol. 28, no. 10, pp. 1126-1140.

Plasma lipid changes in young adult couples consuming polyunsaturated meats and dairy products. / Hodges, R. E.; Salel, A. F.; Dunkley, W. L.; Zelis, Robert; McDonagh, P. F.; Clifford, C.; Hobbs, R. K.; Smith, L. M.; Fan, A.; Mason, D. T.; Lykke, C.

In: American Journal of Clinical Nutrition, Vol. 28, No. 10, 01.12.1975, p. 1126-1140.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Plasma lipid changes in young adult couples consuming polyunsaturated meats and dairy products

AU - Hodges, R. E.

AU - Salel, A. F.

AU - Dunkley, W. L.

AU - Zelis, Robert

AU - McDonagh, P. F.

AU - Clifford, C.

AU - Hobbs, R. K.

AU - Smith, L. M.

AU - Fan, A.

AU - Mason, D. T.

AU - Lykke, C.

PY - 1975/12/1

Y1 - 1975/12/1

N2 - 25 Young couples consumed either a saturated or polyunsaturated fat diet for a 20 wk period. The polyunsaturated beef, lamb, and dried products, high in linoleic acid, were produced by feeding ruminant animals 'protected lipid' feeds which prevent hydrogenation of fats in the rumen. The experimental design provided for 4 dietary groups: A) saturated diet for 20 wk; B) polyunsaturated diet for 20 wk; C) saturated diet for 10 wk then polyunsaturated diet for 10 wk; and D) polyunsaturated for 10 wk and then saturated diet for 10 wk. Polyunsaturated to saturated ratios (linoleic: total saturated fatty acids) for the diets were: prestudy, 0.43-0.56; saturated, 0.11-0.14; polyunsaturated, 0.56-0.62. Factors other than diet that appeared to affect cholesterol responses were carefully considered. During the initial 3 wk (regimentation period) plasma cholesterol concentrations decreased in all groups irrespective of diet. This was followed by 2 experimental periods in which the effects of the prescribed diets were readily apparent (response periods I and II). The final 4 wk of the study were characterized by diminishing compliance with the dietary discipline (abatement period). Subjects in each group (A,B,C,D) were subdivided into high and low on a basis of each group's initial median cholesterol level. Those in the high subgroups were very responsive to dietary changes whereas those in the low subgroups were not. Combined responses of high subjects were: polyunsaturated diet -10.7 mg/dl (P < 0.025), saturated diet, + 7.8 mg/dl (P < 0.05). Combined difference between saturated and polyunsaturated diets was 18.5 mg/dl or approximately a 10% cholesterol difference between the experimental polyunsaturated and saturated diets.

AB - 25 Young couples consumed either a saturated or polyunsaturated fat diet for a 20 wk period. The polyunsaturated beef, lamb, and dried products, high in linoleic acid, were produced by feeding ruminant animals 'protected lipid' feeds which prevent hydrogenation of fats in the rumen. The experimental design provided for 4 dietary groups: A) saturated diet for 20 wk; B) polyunsaturated diet for 20 wk; C) saturated diet for 10 wk then polyunsaturated diet for 10 wk; and D) polyunsaturated for 10 wk and then saturated diet for 10 wk. Polyunsaturated to saturated ratios (linoleic: total saturated fatty acids) for the diets were: prestudy, 0.43-0.56; saturated, 0.11-0.14; polyunsaturated, 0.56-0.62. Factors other than diet that appeared to affect cholesterol responses were carefully considered. During the initial 3 wk (regimentation period) plasma cholesterol concentrations decreased in all groups irrespective of diet. This was followed by 2 experimental periods in which the effects of the prescribed diets were readily apparent (response periods I and II). The final 4 wk of the study were characterized by diminishing compliance with the dietary discipline (abatement period). Subjects in each group (A,B,C,D) were subdivided into high and low on a basis of each group's initial median cholesterol level. Those in the high subgroups were very responsive to dietary changes whereas those in the low subgroups were not. Combined responses of high subjects were: polyunsaturated diet -10.7 mg/dl (P < 0.025), saturated diet, + 7.8 mg/dl (P < 0.05). Combined difference between saturated and polyunsaturated diets was 18.5 mg/dl or approximately a 10% cholesterol difference between the experimental polyunsaturated and saturated diets.

UR - http://www.scopus.com/inward/record.url?scp=0016817145&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016817145&partnerID=8YFLogxK

M3 - Article

C2 - 1237234

AN - SCOPUS:0016817145

VL - 28

SP - 1126

EP - 1140

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

SN - 0002-9165

IS - 10

ER -

Hodges RE, Salel AF, Dunkley WL, Zelis R, McDonagh PF, Clifford C et al. Plasma lipid changes in young adult couples consuming polyunsaturated meats and dairy products. American Journal of Clinical Nutrition. 1975 Dec 1;28(10):1126-1140.