Polydimethylsiloxane-based polyurethanes: Phase-separated morphology and in vitro oxidative biostability

Taeyi Choi, Jadwiga Weksler, Ajay Padsalgikar, Rebeca Hernndez, James Patrick Runt

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Three series of segmented polyurethane block copolymers were synthesized using 4,4′-methylenediphenyl diisocyanate (MDI) and 1,4-butanediol (BDO) or 1,3-bis(4-hydroxybutyl)tetramethyl disiloxane (BHTD) as the hard segments, and soft segments composed of poly(dimethyl siloxane) (PDMS)-based and poly(hexamethylene oxide) (PHMO) macrodiols. Copolymers synthesized with the PDMS macrodiol and PDMS and PHMO macrodiol mixtures consist of three microphases: a PDMS phase, hard domains, and a mixed phase of PHMO (when present), PDMS ether end-group segments and some dissolved hard segments. Degrees of phase separation were characterized using small-angle X-ray scattering by applying a pseudo two-phase model, and the morphology resulting from unlike segment demixing was found to be closely related to the in vitro oxidative biostability of these segmented polyurethanes.

Original languageEnglish (US)
Pages (from-to)794-798
Number of pages5
JournalAustralian Journal of Chemistry
Volume62
Issue number8
DOIs
StatePublished - Aug 27 2009

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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