Polymorphism of t-complex genes in European wild mice

Jan Klein, Peter Sipos, Felipe Figueroa

Research output: Contribution to journalArticle

93 Citations (Scopus)

Abstract

Thirty-two t haplotypes were extracted from wild mice captured in Central Europe, Spain, the Soviet Union, Israel, Egypt, the Orkneys and South and North America, and tested for lethality in the homozygous state. Twenty-two proved to be homozygous lethals, 8 semilethals and 2 viables. The lethal t haplotypes were then tested by the genetic complementation test for identity with representatives of known complementation groups and with each other. Five of the 22 haplotypes proved to carry previously identified lethality factors (t w5 , t w73 , and t Lub-1 ), while the rest carried new factors. The 17 haplotypes fell into 8 new complementation groups. Two of the new groups are partially overlapping in that they seem to share some lethality factors and differ in others. These tests raise the total number of known complementation groups to 16. The distribution of the individual t haplotypes among wild mice populations seems to reflect their differentiation from a common ancestor haplotype.

Original languageEnglish (US)
Pages (from-to)39-46
Number of pages8
JournalGenetical research
Volume44
Issue number1
DOIs
StatePublished - Jan 1 1984

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Haplotypes
Genes
Genetic Complementation Test
South America
USSR
Egypt
Israel
North America
Spain
Population

All Science Journal Classification (ASJC) codes

  • Genetics

Cite this

Klein, Jan ; Sipos, Peter ; Figueroa, Felipe. / Polymorphism of t-complex genes in European wild mice. In: Genetical research. 1984 ; Vol. 44, No. 1. pp. 39-46.
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Polymorphism of t-complex genes in European wild mice. / Klein, Jan; Sipos, Peter; Figueroa, Felipe.

In: Genetical research, Vol. 44, No. 1, 01.01.1984, p. 39-46.

Research output: Contribution to journalArticle

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