Potential Influence of Midgut pH and Redox Potential on Protein Utilization in Insect Herbivores

Kelly S. Johnson, Gary Felton

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Early insect physiologists recognized the importance of gut physicochemistry, primarily pH, redox potential, and ionic strength, on digestive processes, but studies to date have been primarily restricted to keratin- and wood-feeding insects. Recent investigations show that herbivorous insects have a broad range of gut redox conditions, with pHs ranging from 6.0 to 11.8 and measured redox potentials from -200 to +240 mV. The redox state of the gut is largely dependent on pH, which is well regulated, and the redox activity of ingested material, including plant chemicals, at that pH. Inter- and intraspecific variation in midgut redox conditions appears to be substantial enough to affect digestion via effects on the structure and function of dietary proteins and proteolytic enzymes. The impact of reducing conditions on proteins probably depends on characteristics such as tertiary structure and the number and arrangement of disulfide linkages. In addition to the effects of reducing conditions in dietary proteins, there can be effects on the activities of digestive enzymes, depending on their structure and the nature of their catalytic site. We speculate that phylogenetic and environmental determinants of gut physicochemistry may place constraints on the efficacy of different digestive processes, and may thus influence the evolution of digestive strategies in insects.

Original languageEnglish (US)
Pages (from-to)85-105
Number of pages21
JournalArchives of Insect Biochemistry and Physiology
Volume32
Issue number1
DOIs
StatePublished - Jan 1 1996

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Herbivory
redox potential
midgut
Oxidation-Reduction
Insects
herbivores
digestive system
insects
dietary protein
Proteins
proteins
Dietary Proteins
keratin
phytophagous insects
digestive enzymes
ionic strength
physiologists
sulfides
interspecific variation
active sites

All Science Journal Classification (ASJC) codes

  • Physiology
  • Biochemistry
  • Insect Science

Cite this

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Potential Influence of Midgut pH and Redox Potential on Protein Utilization in Insect Herbivores. / Johnson, Kelly S.; Felton, Gary.

In: Archives of Insect Biochemistry and Physiology, Vol. 32, No. 1, 01.01.1996, p. 85-105.

Research output: Contribution to journalArticle

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