Potential stages for prostate cancer prevention with selenium: Implications for cancer survivors

Nicole Facompre, Karam El-Bayoumy

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations

Abstract

The lack of treatment for "worried well" patients with high-grade prostatic intraepithelial neoplasia combined with issues of recurrence and hormone resistance in prostate cancer survivors remains a major public health obstacle. The long latency of prostate cancer development provides an ample opportunity to intervene with mechanistically based chemopreventive agents at various stages of disease progression. Our rationale for selenium intervention is based on current mechanistic knowledge derived solely from preclin-ical investigations. Clearly, there is sufficient scientific support for its entry into current clinical trials, the outcome of which will be highly valuable in assessing whether selenium can be recommended for cancer survivors.

Original languageEnglish (US)
Pages (from-to)2699-2703
Number of pages5
JournalCancer Research
Volume69
Issue number7
DOIs
StatePublished - Apr 1 2009

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Potential stages for prostate cancer prevention with selenium: Implications for cancer survivors'. Together they form a unique fingerprint.

Cite this