Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in North-Eastern Region of India

P. Roychoudhury, D. K. Sarma, S. Rajkhowa, M. Munir, Suresh Varma Kuchipudi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Classical swine fever (CSF) is a highly contagious and the most important disease of pigs worldwide. CSF is enzootic in pig herds in India and continues to cause huge economic losses to pig farmers. Nearly 40% of the total pig population of India is present in the north-eastern (NE) states where pig husbandry plays an important role in the socio-economic development. Pigs reared in the backyards are the only source of livelihood for a majority of poor tribal population in the region. Hardly any CSF vaccination is currently being undertaken in the unorganized pig farming in the NE region due to economic reasons and vaccine unavailability. A thorough understanding of the current epidemiological status of CSF is essential for the effective control of the disease in the NE region. Hence, we carried out molecular characterization of CSFV isolates from field outbreaks during 2011-2012 in the entire north-eastern region of India to establish the genetic groups of prevalent CSF viruses in the region. A total of 17 CSFV isolates obtained from different parts of the NE region were characterized by comparing the sequences of three partial genomic regions of the virus, that is 150nt of 5′ UTR, 190 nt of E2 and 409 nt of NS5B. Of the 17 CSFV isolates, 15 isolates belonged to 1.1 (88.2%) and two isolates (11.8%) belonged to 2.2 subgenogroup. The genogroup 2.2 CSFV were associated with outbreaks in Arunachal Pradesh that shares international borders with Bhutan, Myanmar and China. Genogroup 2.2 CSFV isolated in the present study shared high level of sequence similarity with 2.2 viruses form China, raising the possibility of virus incursion from this region. In summary, we found a continued predominance of 1.1 subgroup and an emergence of 2.2 subgroup CSFV in NE region of India.

Original languageEnglish (US)
Pages (from-to)69-77
Number of pages9
JournalTransboundary and Emerging Diseases
Volume61
Issue numberSUPPL1.
DOIs
StatePublished - Jan 1 2014

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Classical swine fever virus
India
Classical Swine Fever
hog cholera
Swine
Genotype
swine
genotype
viruses
Viruses
Disease Outbreaks
China
Bhutan
socioeconomic development
economics
Economics
swine diseases
Myanmar
5' untranslated regions
livelihood

All Science Journal Classification (ASJC) codes

  • Immunology and Microbiology(all)
  • veterinary(all)

Cite this

@article{efe0fc5ac08a4d0a93b095f8d26fd273,
title = "Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in North-Eastern Region of India",
abstract = "Classical swine fever (CSF) is a highly contagious and the most important disease of pigs worldwide. CSF is enzootic in pig herds in India and continues to cause huge economic losses to pig farmers. Nearly 40{\%} of the total pig population of India is present in the north-eastern (NE) states where pig husbandry plays an important role in the socio-economic development. Pigs reared in the backyards are the only source of livelihood for a majority of poor tribal population in the region. Hardly any CSF vaccination is currently being undertaken in the unorganized pig farming in the NE region due to economic reasons and vaccine unavailability. A thorough understanding of the current epidemiological status of CSF is essential for the effective control of the disease in the NE region. Hence, we carried out molecular characterization of CSFV isolates from field outbreaks during 2011-2012 in the entire north-eastern region of India to establish the genetic groups of prevalent CSF viruses in the region. A total of 17 CSFV isolates obtained from different parts of the NE region were characterized by comparing the sequences of three partial genomic regions of the virus, that is 150nt of 5′ UTR, 190 nt of E2 and 409 nt of NS5B. Of the 17 CSFV isolates, 15 isolates belonged to 1.1 (88.2{\%}) and two isolates (11.8{\%}) belonged to 2.2 subgenogroup. The genogroup 2.2 CSFV were associated with outbreaks in Arunachal Pradesh that shares international borders with Bhutan, Myanmar and China. Genogroup 2.2 CSFV isolated in the present study shared high level of sequence similarity with 2.2 viruses form China, raising the possibility of virus incursion from this region. In summary, we found a continued predominance of 1.1 subgroup and an emergence of 2.2 subgroup CSFV in NE region of India.",
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Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in North-Eastern Region of India. / Roychoudhury, P.; Sarma, D. K.; Rajkhowa, S.; Munir, M.; Kuchipudi, Suresh Varma.

In: Transboundary and Emerging Diseases, Vol. 61, No. SUPPL1., 01.01.2014, p. 69-77.

Research output: Contribution to journalArticle

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AB - Classical swine fever (CSF) is a highly contagious and the most important disease of pigs worldwide. CSF is enzootic in pig herds in India and continues to cause huge economic losses to pig farmers. Nearly 40% of the total pig population of India is present in the north-eastern (NE) states where pig husbandry plays an important role in the socio-economic development. Pigs reared in the backyards are the only source of livelihood for a majority of poor tribal population in the region. Hardly any CSF vaccination is currently being undertaken in the unorganized pig farming in the NE region due to economic reasons and vaccine unavailability. A thorough understanding of the current epidemiological status of CSF is essential for the effective control of the disease in the NE region. Hence, we carried out molecular characterization of CSFV isolates from field outbreaks during 2011-2012 in the entire north-eastern region of India to establish the genetic groups of prevalent CSF viruses in the region. A total of 17 CSFV isolates obtained from different parts of the NE region were characterized by comparing the sequences of three partial genomic regions of the virus, that is 150nt of 5′ UTR, 190 nt of E2 and 409 nt of NS5B. Of the 17 CSFV isolates, 15 isolates belonged to 1.1 (88.2%) and two isolates (11.8%) belonged to 2.2 subgenogroup. The genogroup 2.2 CSFV were associated with outbreaks in Arunachal Pradesh that shares international borders with Bhutan, Myanmar and China. Genogroup 2.2 CSFV isolated in the present study shared high level of sequence similarity with 2.2 viruses form China, raising the possibility of virus incursion from this region. In summary, we found a continued predominance of 1.1 subgroup and an emergence of 2.2 subgroup CSFV in NE region of India.

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