Prenatal cocaine exposure and trajectories of externalizing behavior problems in early childhood: Examining the role of maternal negative affect

Danielle S. Molnar, Ash Levitt, Rina Das Eiden, Pamela Schuetze

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

This study examined the association between prenatal cocaine exposure (PCE) and developmental trajectories of externalizing behavior problems from 18 to 54 months of child age. A hypothesized indirect association between PCE and externalizing trajectories via maternal negative affect was also examined. Caregiving environmental risk and child sex were evaluated as moderators. This study consisted of 196 mother-child dyads recruited at delivery from local area hospitals (107 PCE, 89 non-PCE) and assessed at seven time points across the toddler to preschool periods. Results revealed no direct associations between PCE and externalizing behavior problem trajectories. However, results did indicate that PCE shared a significant indirect relationship with externalizing behavior problem trajectories via higher levels of maternal negative affect. The association between PCE and externalizing problem trajectories was also moderated by caregiving environmental risk such that PCE children in high-risk caregiving environments did not experience the well-documented normative decline in externalizing behavior problems beginning at around 3 years of age. This study suggests potential pathways to externalizing behavior problems among high-risk children.

Original languageEnglish (US)
Pages (from-to)515-528
Number of pages14
JournalDevelopment and Psychopathology
Volume26
Issue number2
DOIs
StatePublished - May 2014

All Science Journal Classification (ASJC) codes

  • Developmental and Educational Psychology
  • Psychiatry and Mental health

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