Preterm infants' sympathetic arousal and associated behavioral responses to sound stimuli in the neonatal intensive care unit

Arash Salavitabar, Kim Kopenhaver Doheny, Cherie S. Adkins, Elizabeth J. Susman, Charles Palmer, Hanne Storm

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

PURPOSE: To evaluate the utility of skin conductance (SC) as a measure of autonomic arousal to sound stimuli in preterm infants. DESIGN: A pilot cross-sectional, correlations study. SUBJECTS: Eleven preterm infants with a mean gestational age of 31.6 weeks without anomalies or conditions associated with neurodevelopmental delay composed the sample. METHODS: On days 5-7 of life, the following infant responses were simultaneously recorded in response to naturally occurring sound stimuli in the NICU: real-time measurements of heart rate, respiratory rate, and oxygen saturations; sympathetic-mediated sweating via SC; and behavioral responses using the Newborn Individualized Developmental Care and Assessment Program naturalistic observation. Baseline sound levels (BSL, <55 dBA) and high sound levels (HSL, >65 dBA) were measured to index patterns of response during a nonhandling period preceding care. RESULTS: Mean heart rate during precare was directly associated with higher SC increases to sound stimuli (r[10] = 0.697, P=.017). The SC during HSL was significantly higher than that during BSL (P<.0001). Males demonstrated higher SC increases to sound stimuli than females (P =.030). Changes in SC induced by increases in sound intensity were associated with lower attention responses (r[10] = -0.92, P <.0001) and lower summated behavioral responses (r[10] = - 0.59, P=.054). CONCLUSION: SC provides a noninvasive, sensitive measure of sympathetic arousal that may not be apparent in behavioral cues or states, or determined by standard physiological responses alone.

Original languageEnglish (US)
Pages (from-to)158-166
Number of pages9
JournalAdvances in Neonatal Care
Volume10
Issue number3
DOIs
StatePublished - Jan 1 2010

Fingerprint

Neonatal Intensive Care Units
Arousal
Premature Infants
Skin
Heart Rate
Sweating
Respiratory Rate
Gestational Age
Cues
Cross-Sectional Studies
Observation
Newborn Infant
Oxygen

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

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title = "Preterm infants' sympathetic arousal and associated behavioral responses to sound stimuli in the neonatal intensive care unit",
abstract = "PURPOSE: To evaluate the utility of skin conductance (SC) as a measure of autonomic arousal to sound stimuli in preterm infants. DESIGN: A pilot cross-sectional, correlations study. SUBJECTS: Eleven preterm infants with a mean gestational age of 31.6 weeks without anomalies or conditions associated with neurodevelopmental delay composed the sample. METHODS: On days 5-7 of life, the following infant responses were simultaneously recorded in response to naturally occurring sound stimuli in the NICU: real-time measurements of heart rate, respiratory rate, and oxygen saturations; sympathetic-mediated sweating via SC; and behavioral responses using the Newborn Individualized Developmental Care and Assessment Program naturalistic observation. Baseline sound levels (BSL, <55 dBA) and high sound levels (HSL, >65 dBA) were measured to index patterns of response during a nonhandling period preceding care. RESULTS: Mean heart rate during precare was directly associated with higher SC increases to sound stimuli (r[10] = 0.697, P=.017). The SC during HSL was significantly higher than that during BSL (P<.0001). Males demonstrated higher SC increases to sound stimuli than females (P =.030). Changes in SC induced by increases in sound intensity were associated with lower attention responses (r[10] = -0.92, P <.0001) and lower summated behavioral responses (r[10] = - 0.59, P=.054). CONCLUSION: SC provides a noninvasive, sensitive measure of sympathetic arousal that may not be apparent in behavioral cues or states, or determined by standard physiological responses alone.",
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Preterm infants' sympathetic arousal and associated behavioral responses to sound stimuli in the neonatal intensive care unit. / Salavitabar, Arash; Doheny, Kim Kopenhaver; Adkins, Cherie S.; Susman, Elizabeth J.; Palmer, Charles; Storm, Hanne.

In: Advances in Neonatal Care, Vol. 10, No. 3, 01.01.2010, p. 158-166.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Preterm infants' sympathetic arousal and associated behavioral responses to sound stimuli in the neonatal intensive care unit

AU - Salavitabar, Arash

AU - Doheny, Kim Kopenhaver

AU - Adkins, Cherie S.

AU - Susman, Elizabeth J.

AU - Palmer, Charles

AU - Storm, Hanne

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N2 - PURPOSE: To evaluate the utility of skin conductance (SC) as a measure of autonomic arousal to sound stimuli in preterm infants. DESIGN: A pilot cross-sectional, correlations study. SUBJECTS: Eleven preterm infants with a mean gestational age of 31.6 weeks without anomalies or conditions associated with neurodevelopmental delay composed the sample. METHODS: On days 5-7 of life, the following infant responses were simultaneously recorded in response to naturally occurring sound stimuli in the NICU: real-time measurements of heart rate, respiratory rate, and oxygen saturations; sympathetic-mediated sweating via SC; and behavioral responses using the Newborn Individualized Developmental Care and Assessment Program naturalistic observation. Baseline sound levels (BSL, <55 dBA) and high sound levels (HSL, >65 dBA) were measured to index patterns of response during a nonhandling period preceding care. RESULTS: Mean heart rate during precare was directly associated with higher SC increases to sound stimuli (r[10] = 0.697, P=.017). The SC during HSL was significantly higher than that during BSL (P<.0001). Males demonstrated higher SC increases to sound stimuli than females (P =.030). Changes in SC induced by increases in sound intensity were associated with lower attention responses (r[10] = -0.92, P <.0001) and lower summated behavioral responses (r[10] = - 0.59, P=.054). CONCLUSION: SC provides a noninvasive, sensitive measure of sympathetic arousal that may not be apparent in behavioral cues or states, or determined by standard physiological responses alone.

AB - PURPOSE: To evaluate the utility of skin conductance (SC) as a measure of autonomic arousal to sound stimuli in preterm infants. DESIGN: A pilot cross-sectional, correlations study. SUBJECTS: Eleven preterm infants with a mean gestational age of 31.6 weeks without anomalies or conditions associated with neurodevelopmental delay composed the sample. METHODS: On days 5-7 of life, the following infant responses were simultaneously recorded in response to naturally occurring sound stimuli in the NICU: real-time measurements of heart rate, respiratory rate, and oxygen saturations; sympathetic-mediated sweating via SC; and behavioral responses using the Newborn Individualized Developmental Care and Assessment Program naturalistic observation. Baseline sound levels (BSL, <55 dBA) and high sound levels (HSL, >65 dBA) were measured to index patterns of response during a nonhandling period preceding care. RESULTS: Mean heart rate during precare was directly associated with higher SC increases to sound stimuli (r[10] = 0.697, P=.017). The SC during HSL was significantly higher than that during BSL (P<.0001). Males demonstrated higher SC increases to sound stimuli than females (P =.030). Changes in SC induced by increases in sound intensity were associated with lower attention responses (r[10] = -0.92, P <.0001) and lower summated behavioral responses (r[10] = - 0.59, P=.054). CONCLUSION: SC provides a noninvasive, sensitive measure of sympathetic arousal that may not be apparent in behavioral cues or states, or determined by standard physiological responses alone.

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