Preterm infants' sympathetic arousal and associated behavioral responses to sound stimuli in the neonatal intensive care unit

Arash Salavitabar, Kim Kopenhaver Haidet, Cherie S. Adkins, Elizabeth J. Susman, Charles Palmer, Hanne Storm

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

PURPOSE: To evaluate the utility of skin conductance (SC) as a measure of autonomic arousal to sound stimuli in preterm infants. DESIGN: A pilot cross-sectional, correlations study. SUBJECTS: Eleven preterm infants with a mean gestational age of 31.6 weeks without anomalies or conditions associated with neurodevelopmental delay composed the sample. METHODS: On days 5-7 of life, the following infant responses were simultaneously recorded in response to naturally occurring sound stimuli in the NICU: real-time measurements of heart rate, respiratory rate, and oxygen saturations; sympathetic-mediated sweating via SC; and behavioral responses using the Newborn Individualized Developmental Care and Assessment Program naturalistic observation. Baseline sound levels (BSL, <55 dBA) and high sound levels (HSL, >65 dBA) were measured to index patterns of response during a nonhandling period preceding care. RESULTS: Mean heart rate during precare was directly associated with higher SC increases to sound stimuli (r[10] = 0.697, P=.017). The SC during HSL was significantly higher than that during BSL (P<.0001). Males demonstrated higher SC increases to sound stimuli than females (P =.030). Changes in SC induced by increases in sound intensity were associated with lower attention responses (r[10] = -0.92, P <.0001) and lower summated behavioral responses (r[10] = - 0.59, P=.054). CONCLUSION: SC provides a noninvasive, sensitive measure of sympathetic arousal that may not be apparent in behavioral cues or states, or determined by standard physiological responses alone.

Original languageEnglish (US)
Pages (from-to)158-166
Number of pages9
JournalAdvances in Neonatal Care
Volume10
Issue number3
DOIs
StatePublished - Jun 2010

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

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