The elderly may run a special risk of anticholinergic drug toxicity due to polypharmacy. A 30% sample of the prescription records of 330,000 elderly individuals enrolled in the Pennsylvania Pharmaceutical Assistance Contract for the Elderly (PACE) Program during the 1985-86 year were analyzed for the prevalence of concurrent use of anticholinergic drugs by residential status, age, sex, and medicine use. A total of 393 generic drugs and generic drug compounds with anticholinergic properties were identified in 31 therapeutic categories (AHFS) accounting for 547 drug product names. Anticholinergic drugs constitute 8.8% of PACE claims volume. There were 6,703 persons, 8.7% of the community sample and 20% of the nursing home sample, that used two or more anticholinergic drugs. Total medicine use was the strongest predictor of concurrent anticholinergic use.
|Original language||English (US)|
|Number of pages||14|
|Journal||Journal of Geriatric Drug Therapy|
|State||Published - Dec 1 1990|
All Science Journal Classification (ASJC) codes
- Geriatrics and Gerontology
- Pharmacology (medical)