Primary care influenza-like illness surveillance in Ho Chi Minh City, Vietnam 2013-2015

Stacy Todd, Nguyen Thi Cam Huong, Nguyen Thi Le Thanh, Nguyen Ha Thao Vy, Nguyen Thanh Hung, Tran Thi Nhu Thao, Huynh Thi Phuong, Rogier van Doorn, Vu Thi Ty Hang, Nguyen Van Vinh Chau, Jonathan M. Read, David G. Lalloo, Maciej F. Boni

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Year-round transmission of influenza has been detected in Vietnam through both national surveillance and other epidemiological studies. Understanding the demographic and clinical features of influenza-like illness (ILI) presenting to primary care in urban Vietnam is vital to understand these transmission dynamics. Methods: An observational study of patients with ILI in Ho Chi Minh City, Vietnam, was conducted between August 2013 and November 2015 in a mix of public and private primary care settings. Molecular testing for influenza A and influenza B and 12 other respiratory viruses was performed. Results: A total of 1152 ILI patients were recruited. 322 and 136 subjects tested positive for influenza A and influenza B, respectively. 193 subjects tested positive for another respiratory virus; most commonly rhinovirus and parainfluenza virus 3. Influenza was detected in 81% of the 116 study weeks. Three peaks of influenza activity were detected; an H3N2 peak April-June 2014, an influenza B peak July-December 2014, and a mixed H3N2 and H1N1 peak March-September 2015. Subjects recruited from private clinics were more likely to have higher income and to have reported previous influenza vaccination. Antibiotic use was common (50.3%) despite limited evidence of bacterial infection. Conclusion: Influenza in southern Vietnam has complex transmission dynamics including periods of intense influenza activity of alternating types and subtypes. Broadening surveillance from hospital to the community in tropical settings is feasible and a valuable for improving our understanding of the global spread and evolution of the virus.

Original languageEnglish (US)
Pages (from-to)623-631
Number of pages9
JournalInfluenza and other Respiratory Viruses
Volume12
Issue number5
DOIs
StatePublished - Sep 2018

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Vietnam
Human Influenza
Primary Health Care
Viruses
Paramyxoviridae Infections
Rhinovirus
Bacterial Infections
Observational Studies
Epidemiologic Studies
Vaccination

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Pulmonary and Respiratory Medicine
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

Todd, Stacy ; Huong, Nguyen Thi Cam ; Thanh, Nguyen Thi Le ; Vy, Nguyen Ha Thao ; Hung, Nguyen Thanh ; Thao, Tran Thi Nhu ; Phuong, Huynh Thi ; van Doorn, Rogier ; Hang, Vu Thi Ty ; Chau, Nguyen Van Vinh ; Read, Jonathan M. ; Lalloo, David G. ; Boni, Maciej F. / Primary care influenza-like illness surveillance in Ho Chi Minh City, Vietnam 2013-2015. In: Influenza and other Respiratory Viruses. 2018 ; Vol. 12, No. 5. pp. 623-631.
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title = "Primary care influenza-like illness surveillance in Ho Chi Minh City, Vietnam 2013-2015",
abstract = "Background: Year-round transmission of influenza has been detected in Vietnam through both national surveillance and other epidemiological studies. Understanding the demographic and clinical features of influenza-like illness (ILI) presenting to primary care in urban Vietnam is vital to understand these transmission dynamics. Methods: An observational study of patients with ILI in Ho Chi Minh City, Vietnam, was conducted between August 2013 and November 2015 in a mix of public and private primary care settings. Molecular testing for influenza A and influenza B and 12 other respiratory viruses was performed. Results: A total of 1152 ILI patients were recruited. 322 and 136 subjects tested positive for influenza A and influenza B, respectively. 193 subjects tested positive for another respiratory virus; most commonly rhinovirus and parainfluenza virus 3. Influenza was detected in 81{\%} of the 116 study weeks. Three peaks of influenza activity were detected; an H3N2 peak April-June 2014, an influenza B peak July-December 2014, and a mixed H3N2 and H1N1 peak March-September 2015. Subjects recruited from private clinics were more likely to have higher income and to have reported previous influenza vaccination. Antibiotic use was common (50.3{\%}) despite limited evidence of bacterial infection. Conclusion: Influenza in southern Vietnam has complex transmission dynamics including periods of intense influenza activity of alternating types and subtypes. Broadening surveillance from hospital to the community in tropical settings is feasible and a valuable for improving our understanding of the global spread and evolution of the virus.",
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Todd, S, Huong, NTC, Thanh, NTL, Vy, NHT, Hung, NT, Thao, TTN, Phuong, HT, van Doorn, R, Hang, VTT, Chau, NVV, Read, JM, Lalloo, DG & Boni, MF 2018, 'Primary care influenza-like illness surveillance in Ho Chi Minh City, Vietnam 2013-2015', Influenza and other Respiratory Viruses, vol. 12, no. 5, pp. 623-631. https://doi.org/10.1111/irv.12574

Primary care influenza-like illness surveillance in Ho Chi Minh City, Vietnam 2013-2015. / Todd, Stacy; Huong, Nguyen Thi Cam; Thanh, Nguyen Thi Le; Vy, Nguyen Ha Thao; Hung, Nguyen Thanh; Thao, Tran Thi Nhu; Phuong, Huynh Thi; van Doorn, Rogier; Hang, Vu Thi Ty; Chau, Nguyen Van Vinh; Read, Jonathan M.; Lalloo, David G.; Boni, Maciej F.

In: Influenza and other Respiratory Viruses, Vol. 12, No. 5, 09.2018, p. 623-631.

Research output: Contribution to journalArticle

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T1 - Primary care influenza-like illness surveillance in Ho Chi Minh City, Vietnam 2013-2015

AU - Todd, Stacy

AU - Huong, Nguyen Thi Cam

AU - Thanh, Nguyen Thi Le

AU - Vy, Nguyen Ha Thao

AU - Hung, Nguyen Thanh

AU - Thao, Tran Thi Nhu

AU - Phuong, Huynh Thi

AU - van Doorn, Rogier

AU - Hang, Vu Thi Ty

AU - Chau, Nguyen Van Vinh

AU - Read, Jonathan M.

AU - Lalloo, David G.

AU - Boni, Maciej F.

PY - 2018/9

Y1 - 2018/9

N2 - Background: Year-round transmission of influenza has been detected in Vietnam through both national surveillance and other epidemiological studies. Understanding the demographic and clinical features of influenza-like illness (ILI) presenting to primary care in urban Vietnam is vital to understand these transmission dynamics. Methods: An observational study of patients with ILI in Ho Chi Minh City, Vietnam, was conducted between August 2013 and November 2015 in a mix of public and private primary care settings. Molecular testing for influenza A and influenza B and 12 other respiratory viruses was performed. Results: A total of 1152 ILI patients were recruited. 322 and 136 subjects tested positive for influenza A and influenza B, respectively. 193 subjects tested positive for another respiratory virus; most commonly rhinovirus and parainfluenza virus 3. Influenza was detected in 81% of the 116 study weeks. Three peaks of influenza activity were detected; an H3N2 peak April-June 2014, an influenza B peak July-December 2014, and a mixed H3N2 and H1N1 peak March-September 2015. Subjects recruited from private clinics were more likely to have higher income and to have reported previous influenza vaccination. Antibiotic use was common (50.3%) despite limited evidence of bacterial infection. Conclusion: Influenza in southern Vietnam has complex transmission dynamics including periods of intense influenza activity of alternating types and subtypes. Broadening surveillance from hospital to the community in tropical settings is feasible and a valuable for improving our understanding of the global spread and evolution of the virus.

AB - Background: Year-round transmission of influenza has been detected in Vietnam through both national surveillance and other epidemiological studies. Understanding the demographic and clinical features of influenza-like illness (ILI) presenting to primary care in urban Vietnam is vital to understand these transmission dynamics. Methods: An observational study of patients with ILI in Ho Chi Minh City, Vietnam, was conducted between August 2013 and November 2015 in a mix of public and private primary care settings. Molecular testing for influenza A and influenza B and 12 other respiratory viruses was performed. Results: A total of 1152 ILI patients were recruited. 322 and 136 subjects tested positive for influenza A and influenza B, respectively. 193 subjects tested positive for another respiratory virus; most commonly rhinovirus and parainfluenza virus 3. Influenza was detected in 81% of the 116 study weeks. Three peaks of influenza activity were detected; an H3N2 peak April-June 2014, an influenza B peak July-December 2014, and a mixed H3N2 and H1N1 peak March-September 2015. Subjects recruited from private clinics were more likely to have higher income and to have reported previous influenza vaccination. Antibiotic use was common (50.3%) despite limited evidence of bacterial infection. Conclusion: Influenza in southern Vietnam has complex transmission dynamics including periods of intense influenza activity of alternating types and subtypes. Broadening surveillance from hospital to the community in tropical settings is feasible and a valuable for improving our understanding of the global spread and evolution of the virus.

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