Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP

Gordon F. Buchanan; Bruce J. Gluckman; Franck K. Kalume; Samden Lhatoo; Rama K. Maganti; Jeffrey L. Noebels; Kristina A. Simeone; Mark S. Quigg; Milena K. Pavlova

doi:10.1177/15357597211004556

Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP

Gordon F. Buchanan, Bruce J. Gluckman, Franck K. Kalume, Samden Lhatoo, Rama K. Maganti, Jeffrey L. Noebels, Kristina A. Simeone, Mark S. Quigg, Milena K. Pavlova

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients with refractory epilepsy. Likely pathophysiological mechanisms include seizure-induced cardiac and respiratory dysregulation. A frequently identified feature in SUDEP cases is that they occur at night. This raises the question of a role for sleep state in regulating of SUDEP. An association with sleep has been identified in a number of studies with patients and in animal models. The focus of this section of the Sleep and Epilepsy Workshop was on identifying and understanding the role for sleep and time of day in the pathophysiology of SUDEP.

Original language	English (US)
Pages (from-to)	215-219
Number of pages	5
Journal	Epilepsy Currents
Volume	21
Issue number	3
DOIs	https://doi.org/10.1177/15357597211004556
State	Published - May 2021

All Science Journal Classification (ASJC) codes

Clinical Neurology

Access to Document

10.1177/15357597211004556

Cite this

@article{ef70f11b862047aca08da90289887d74,

title = "Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP",

abstract = "Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients with refractory epilepsy. Likely pathophysiological mechanisms include seizure-induced cardiac and respiratory dysregulation. A frequently identified feature in SUDEP cases is that they occur at night. This raises the question of a role for sleep state in regulating of SUDEP. An association with sleep has been identified in a number of studies with patients and in animal models. The focus of this section of the Sleep and Epilepsy Workshop was on identifying and understanding the role for sleep and time of day in the pathophysiology of SUDEP.",

author = "Buchanan, {Gordon F.} and Gluckman, {Bruce J.} and Kalume, {Franck K.} and Samden Lhatoo and Maganti, {Rama K.} and Noebels, {Jeffrey L.} and Simeone, {Kristina A.} and Quigg, {Mark S.} and Pavlova, {Milena K.}",

note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The Sleep and Epilepsy Workshop was supported in part by a grant from the BAND Foundation. Publisher Copyright: {\textcopyright} The Author(s) 2021.",

year = "2021",

month = may,

doi = "10.1177/15357597211004556",

language = "English (US)",

volume = "21",

pages = "215--219",

journal = "Epilepsy Currents",

issn = "1535-7597",

publisher = "American Epilepsy Society",

number = "3",

}

TY - JOUR

T1 - Proceedings of the Sleep and Epilepsy Workshop

T2 - Section 3 Mortality: Sleep, Night, and SUDEP

AU - Buchanan, Gordon F.

AU - Gluckman, Bruce J.

AU - Kalume, Franck K.

AU - Lhatoo, Samden

AU - Maganti, Rama K.

AU - Noebels, Jeffrey L.

AU - Simeone, Kristina A.

AU - Quigg, Mark S.

AU - Pavlova, Milena K.

N1 - Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The Sleep and Epilepsy Workshop was supported in part by a grant from the BAND Foundation. Publisher Copyright: © The Author(s) 2021.

PY - 2021/5

Y1 - 2021/5

N2 - Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients with refractory epilepsy. Likely pathophysiological mechanisms include seizure-induced cardiac and respiratory dysregulation. A frequently identified feature in SUDEP cases is that they occur at night. This raises the question of a role for sleep state in regulating of SUDEP. An association with sleep has been identified in a number of studies with patients and in animal models. The focus of this section of the Sleep and Epilepsy Workshop was on identifying and understanding the role for sleep and time of day in the pathophysiology of SUDEP.

AB - Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients with refractory epilepsy. Likely pathophysiological mechanisms include seizure-induced cardiac and respiratory dysregulation. A frequently identified feature in SUDEP cases is that they occur at night. This raises the question of a role for sleep state in regulating of SUDEP. An association with sleep has been identified in a number of studies with patients and in animal models. The focus of this section of the Sleep and Epilepsy Workshop was on identifying and understanding the role for sleep and time of day in the pathophysiology of SUDEP.

UR - http://www.scopus.com/inward/record.url?scp=85103844622&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85103844622&partnerID=8YFLogxK

U2 - 10.1177/15357597211004556

DO - 10.1177/15357597211004556

M3 - Article

C2 - 33787378

AN - SCOPUS:85103844622

SN - 1535-7597

VL - 21

SP - 215

EP - 219

JO - Epilepsy Currents

JF - Epilepsy Currents

IS - 3

ER -

Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this