Production and application of menaquinone-7 (vitamin K2): a new perspective

Ehsan Mahdinia, Ali Demirci, Aydin Berenjian

Research output: Contribution to journalReview article

18 Citations (Scopus)

Abstract

Menaquinone-7, a highly valuable member of the vitamin K series, has significant effects on preventing osteoporosis and cardiovascular disease besides its positive effects on blood coagulation. In this review, chemical and biological aspects of menaquinone-7 are briefly summarized followed by a critical review on upstream and downstream processing developments for its production and recovery, including solid versus liquid fermentations, static versus agitated fermentations and online versus post-production recovery. Latest research outcomes for improving industrial scale production of menaquinone-7 are summarized and recommendations are given for areas of future research.

Original languageEnglish (US)
Article number2
JournalWorld Journal of Microbiology and Biotechnology
Volume33
Issue number1
DOIs
StatePublished - Jan 1 2017

Fingerprint

Vitamin K 2
Fermentation
Vitamin K
Blood Coagulation
Osteoporosis
Cardiovascular Diseases
Outcome Assessment (Health Care)
vitamin MK 7

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Physiology
  • Applied Microbiology and Biotechnology

Cite this

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Production and application of menaquinone-7 (vitamin K2) : a new perspective. / Mahdinia, Ehsan; Demirci, Ali; Berenjian, Aydin.

In: World Journal of Microbiology and Biotechnology, Vol. 33, No. 1, 2, 01.01.2017.

Research output: Contribution to journalReview article

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