Production of Specific Antisera to Human B Lymphocytes

Peter Goodfellow, Colin Barnstable, Elizabeth Jones, Walter F. Bodmer, Michael J. Crumpton, David Snary

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Antisera have been prepared, in mice and rabbits, to membrane and sub‐membrane fractions of human B lymphocyte derived lymphoid lines. Antisera to a protein subfraction were, after only minimal absorption, specific for human peripheral B lymphocytes, monocytes and B cell derived lymphoid lines. The antigen(s) recognised by these antisera were not the same as the previously described B‐cell markers; immunoglobulin, Fc receptor, complement receptor and Ia antigens. The antigen(s) could not be removed from cells by lysostrip with anti‐ β2 microglobulin.

Original languageEnglish (US)
Pages (from-to)105-117
Number of pages13
JournalTissue Antigens
Volume7
Issue number2
DOIs
StatePublished - Feb 1976

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Biochemistry
  • Genetics

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  • Cite this

    Goodfellow, P., Barnstable, C., Jones, E., Bodmer, W. F., Crumpton, M. J., & Snary, D. (1976). Production of Specific Antisera to Human B Lymphocytes. Tissue Antigens, 7(2), 105-117. https://doi.org/10.1111/j.1399-0039.1976.tb01039.x