Programmable diagnostic devices made from paper and tape

Andres W. Martinez, Scott T. Phillips, Zhihong Nie, Chao Min Cheng, Emanuel Carrilho, Benjamin J. Wiley, George M. Whitesides

Research output: Contribution to journalArticle

245 Citations (Scopus)

Abstract

This paper describes three-dimensional microfluidic paper-based analytical devices (3-D PADs) that can be programmed (postfabrication) by the user to generate multiple patterns of flow through them. These devices are programmed by pressing single-use 'on' buttons, using a stylus or a ballpoint pen. Pressing a button closes a small space (gap) between two vertically aligned microfluidic channels, and allows fluids to wick from one channel to the other. These devices are simple to fabricate, and are made entirely out of paper and double-sided adhesive tape. Programmable devices expand the capabilities of PADs and provide a simple method for controlling the movement of fluids in paper-based channels. They are the conceptual equivalent of field-programmable gate arrays (FPGAs) widely used in electronics.

Original languageEnglish (US)
Pages (from-to)2499-2504
Number of pages6
JournalLab on a Chip
Volume10
Issue number19
DOIs
StatePublished - Oct 7 2010

Fingerprint

Microfluidics
Tapes
Equipment and Supplies
Fluids
Field programmable gate arrays (FPGA)
Adhesives
Electronic equipment
Capillary Action

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

Cite this

Martinez, A. W., Phillips, S. T., Nie, Z., Cheng, C. M., Carrilho, E., Wiley, B. J., & Whitesides, G. M. (2010). Programmable diagnostic devices made from paper and tape. Lab on a Chip, 10(19), 2499-2504. https://doi.org/10.1039/c0lc00021c
Martinez, Andres W. ; Phillips, Scott T. ; Nie, Zhihong ; Cheng, Chao Min ; Carrilho, Emanuel ; Wiley, Benjamin J. ; Whitesides, George M. / Programmable diagnostic devices made from paper and tape. In: Lab on a Chip. 2010 ; Vol. 10, No. 19. pp. 2499-2504.
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Martinez, AW, Phillips, ST, Nie, Z, Cheng, CM, Carrilho, E, Wiley, BJ & Whitesides, GM 2010, 'Programmable diagnostic devices made from paper and tape', Lab on a Chip, vol. 10, no. 19, pp. 2499-2504. https://doi.org/10.1039/c0lc00021c

Programmable diagnostic devices made from paper and tape. / Martinez, Andres W.; Phillips, Scott T.; Nie, Zhihong; Cheng, Chao Min; Carrilho, Emanuel; Wiley, Benjamin J.; Whitesides, George M.

In: Lab on a Chip, Vol. 10, No. 19, 07.10.2010, p. 2499-2504.

Research output: Contribution to journalArticle

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Martinez AW, Phillips ST, Nie Z, Cheng CM, Carrilho E, Wiley BJ et al. Programmable diagnostic devices made from paper and tape. Lab on a Chip. 2010 Oct 7;10(19):2499-2504. https://doi.org/10.1039/c0lc00021c