Prolonged Bleeding Times and Bleeding Diathesis Associated With Moxalactam Administration

Michael R. Weitekamp, Robert C. Aber

Research output: Contribution to journalArticle

151 Scopus citations

Abstract

A reversible bleeding diathesis associated with marked prolongation of the bleeding time was recognized in five patients receiving the new antibiotic moxalactam disodium (Moxam). Platelet dysfunction secondary to interference with adenosine diphosphate-induced aggregation has been demonstrated in vitro. Clinically important hemorrhage consequent to the use of this antibiotic may be more common than previously thought.

Original languageEnglish (US)
Pages (from-to)69-71
Number of pages3
JournalJAMA: The Journal of the American Medical Association
Volume249
Issue number1
DOIs
Publication statusPublished - Jan 7 1983

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this