Prolonged mechanical support of the left ventricle.

W. S. Pierce, J. H. Donachy, D. L. Landis, J. A. Brighton, Gerson Rosenberg, J. J. Migliore, G. A. Prophet, W. J. White, J. A. Waldhausen

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

An interdisciplinary group has developed a left ventricular assist pump system composed of a modified sac type pump, a pneumatic power unit, and a synchronizer. The pump fills from the left ventricle and discharges into the aorta. The system was employed for left ventricular assistance in a series of 12 normal calves, with an average pumping period of 70 +/- 8 days. The system was then evaluated in a series of calves in whom profound left ventricular failure had been produced. These studies indicate that the assist pump is effective in supporting the circulation and completely unloading the left ventricle. The assist system has now been employed in four patients who could not be weaned from cardiopulmonary bypass following cardiac valve replacement. The assist pump supported the circulation in three instances. In one patient, the assist pump was employed for 8 days until left ventricular function had improved sufficiently to permit pump removal; the patient was subsequently discharged from the hospital.

Original languageEnglish (US)
JournalCirculation
Volume58
Issue number3 Pt 2
StatePublished - Jan 1 1978

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Heart Ventricles
Heart Valves
Cardiopulmonary Bypass
Left Ventricular Function
Aorta

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Pierce, W. S., Donachy, J. H., Landis, D. L., Brighton, J. A., Rosenberg, G., Migliore, J. J., ... Waldhausen, J. A. (1978). Prolonged mechanical support of the left ventricle. Circulation, 58(3 Pt 2).
Pierce, W. S. ; Donachy, J. H. ; Landis, D. L. ; Brighton, J. A. ; Rosenberg, Gerson ; Migliore, J. J. ; Prophet, G. A. ; White, W. J. ; Waldhausen, J. A. / Prolonged mechanical support of the left ventricle. In: Circulation. 1978 ; Vol. 58, No. 3 Pt 2.
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Pierce, WS, Donachy, JH, Landis, DL, Brighton, JA, Rosenberg, G, Migliore, JJ, Prophet, GA, White, WJ & Waldhausen, JA 1978, 'Prolonged mechanical support of the left ventricle.', Circulation, vol. 58, no. 3 Pt 2.

Prolonged mechanical support of the left ventricle. / Pierce, W. S.; Donachy, J. H.; Landis, D. L.; Brighton, J. A.; Rosenberg, Gerson; Migliore, J. J.; Prophet, G. A.; White, W. J.; Waldhausen, J. A.

In: Circulation, Vol. 58, No. 3 Pt 2, 01.01.1978.

Research output: Contribution to journalArticle

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Pierce WS, Donachy JH, Landis DL, Brighton JA, Rosenberg G, Migliore JJ et al. Prolonged mechanical support of the left ventricle. Circulation. 1978 Jan 1;58(3 Pt 2).