Abstract
A proteomic approach proposed for identifying the changes in E.coli, metabolically engineered for improved degradation of trichloroethylene (TCE) was investigated. In the metabolic engineering approach to improve aerobic biodegradation, toluene ortho-monoxygenase (TOM)-Green, glutathione S-transferase (GST) and GSHI were co-expressed in E.coli. The genetic manipulations resulted in a variety of physiological changes in the bacterial cells. These changes were found to improve the performance of these microorganisms to degrade pollutants and toxics.
| Original language | English (US) |
|---|---|
| Title of host publication | 2004 AIChE Annual Meeting, Conference Proceedings |
| Pages | 1913-1914 |
| Number of pages | 2 |
| State | Published - 2004 |
| Event | 2004 AIChE Annual Meeting - Austin, TX, United States Duration: Nov 7 2004 → Nov 12 2004 |
Other
| Other | 2004 AIChE Annual Meeting |
|---|---|
| Country | United States |
| City | Austin, TX |
| Period | 11/7/04 → 11/12/04 |
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All Science Journal Classification (ASJC) codes
- Engineering(all)
Cite this
Lacerda, C. M. R., Reardon, K. F., Rui, L., & Wood, T. K. (2004). Proposal to present #12e: A proteomic approach to identify physiological changes in e. coli metabolically engineered for enhanced tce degradation and toxicity reduction. In 2004 AIChE Annual Meeting, Conference Proceedings (pp. 1913-1914). [12e]